中山大学学报（医学科学版）2012，Vol.33Issue(2)：235-240,6.
放疗后中耳胆固醇肉芽肿的治疗
Cholesterin Granuloma of the Middle Ear in Post-irradiated Patients
摘要
Abstract
[Objective] To evaluate the surgical outcome of mastoidectomy plus tympanoplasty for cholesterin granuloma of the middle ear in post-irradiated patients. [Methods] Nine ears diagnosed cholesterin granuloma in the middle ear in post-irradiated NPC patients were included in this study. The time from radiotherapy termination to surgery ranged from 6 to 14 years (median 9 years). All the patients with NPC received radiotherapy of 68 to 75 Gy before surgery. All patients underwent radical tympanoplasty plus mastoidectomy with canal wall down or up. Three ears underwent canal wall down mastoidectomy plus tympanoplasty and six ears underwent canal wall up mastoidectomy plus tympanoplasty. [Results] All the patients were followed up for 2 years at least. There were 7 ears (77.8%) had intact tympanic membrane and 2 ears developed reperforation of eardrum 3 months after surgery, but otorrhea decreased significantly. All these patients reported improved quality of daily life after the surgery. The pure tone average (PTA) of pre-operation was 90.5 dB and air-bone gap (A-B gap) was 45.8 dB respectively versus 62.3 dB and 25.5 dB postoperation 6 months. [Conclusion] Most of post-irradiated NPC patients with cholesterin granuloma of the middle ear benefit from the surgery. Chronic otitis media caused by radiotherapy is not a contraindication to tympanoplasty.关键词
放射治疗/中耳胆固醇肉芽肿/手术Key words
radiotherapy/ cholesterin granuloma of middle ear/ surgery分类
医药卫生引用本文复制引用
杨海弟,许耀东,张志钢,陈穗俊,郑亿庆..放疗后中耳胆固醇肉芽肿的治疗[J].中山大学学报（医学科学版）,2012,33(2):235-240,6.基金项目
广东省科技计划项目(E002006035) （E002006035）
