中国中西医结合杂志2012，Vol.32Issue(3)：325-328,4.
心肝宝胶囊治疗慢性乙型肝炎肝纤维化临床研究
Clinical Research of Xinganbao Capsule on the Treatment of Chronic Hepatitis B Liver Fibrosis
王宪波 1江宇泳 1赵彩彦 2王晓静 1刘芳 2王亚东 2成军1
作者信息
- 1. 首都医科大学附属北京地坛医院中西医结合中心 北京100015
- 2. 河北医科大学附属三院感染科 石家庄050051
- 折叠
摘要
Abstract
Objective To explore the effects of Xinganbao Capsule (Cordyceps Sinensis) on the chronic hepatitis B liver fibrosis. Methods Sixty patients with chronic hepatitis B were randomly assigned to the trail group (40 cases) and the control group (20 cases). The trail group was treated with Xinganbao Capsule, 8 capsules each time, three times a day. The control group was given Heluo Shugan Tablet, 5 pills each time, thrice daily. Six months consisted of one therapeutic course. The liver function, four indicators of serum fibrosis, liver histology, and other items were detected. Results Xinganbao Capsule could reduce serum ALT and AST levels, serum HA, PC-III and LN levels (all P<0.05), showing statistical difference when compared with before treatment. The HA and LN levels decreased more significantly in the control group when compared with before treatment (P<0.05). Totally 21 patients (53% of the recruited cases) in the trial group completed the liver biopsy twice. After treated with Xinganbao Capsule, 81% patients (17/21) had decreased liver inflammation 1 grade or more, 52% patients (11/21) had decreased fibrosis staging one or more, and 33% (7/21) patients had no change in fibrosis. Conclusion Xinganbao Capsule could improve the liver function, reduce liver inflammation, and fight against hepatic fibrosis.关键词
心肝宝胶囊/乙型肝炎/肝纤维化Key words
Xinganbao Capsule/hepatitis B/liver fibrosis引用本文复制引用
王宪波,江宇泳,赵彩彦,王晓静,刘芳,王亚东,成军..心肝宝胶囊治疗慢性乙型肝炎肝纤维化临床研究[J].中国中西医结合杂志,2012,32(3):325-328,4.
