北京大学学报（医学版）2012，Vol.44Issue(3)：397-402,6.DOI:10.3969/j.issn.1671-167X.2012.03.014
采用欧洲五维健康量表测量北京郊区老年人健康效用的实证研究
Empirical research of measuring elderly health utility in the outskirts of Beijing by using European quality of life 5-dimensions
摘要
Abstract
Objective: To evaluate health utility values of the elderly in the outskirts of Beijing by European quality of life 5-dimensions (EQ-5D) from the EuroQol Croup, and to compare the health utility values by using different translation models. Methods: In the cross-sectional study, EQ-5D was used to measure the quality of life for 65 to 79 year-old usual residents in the town of Qinglonghu and Zhoukoudi-an in Fangshan District of Beijing. The health index which represented the health utility was calculated by using the Japan, the United Kingdom (UK) , the United States (US) population-based time trade-off (TTO) modelso Kruskal-Wallis H test was adopted to compare the health indexes calculated by the different models, and intraclass correlations coefficients (ICCs) and Bland-Altman plot were used to evaluate the consistency of the utility calculated by the three models. Mann-Whitney U test was used to compare the impacts of Cardio-vascular diseasel (CVD) on the 3 kinds of health index. The Spearman rho correlation coefficients between the 3 kinds of health index, EQ-VAS (visual analogue scales) score and age, gender, health status were also calculated. Results; There were 2 406 participants in this analysis, with a mean age of 70. 3 years, of whom 34.3% were male. The median and quantile range of Japan weights, US weights and UK weights health indexes were 1 (0. 28) , 1 (0. 24) and 1 (0. 29), respectively. The minimum and maximum of the three indexes were -0.06/1, -0.43/1 and -0.03/ 1, respectively. The US weights yielded the highest scores and the UK weights the lowest scores. The Japan, US and UK weight scores differed from each other (P<0.005). The Japan and US scores had the highest ICCs (0.987, 95% CI 0.986 -0.988), followed by the US and UK scores (0.941, 95% CI 0.937 -0.946) and then the Japan and UK scores (0. 921, 95% CI 0. 915 -0. 927). The difference scores of 96. 9% , 95. 1% and 95. 0% were found between the limits of agreement in Bland-Altmand plot. Negative correlations existed between the US/UK score and the number of CVDs, but not existed between the Japan score and the number of CVDs. Conclusion; The health indexes calculated by using the different EQ-5D TTO transform models were different for the elderly people in the Beijing suburban district, TTO model based on Chinese health preference should be developed.关键词
生活质量/健康状况指标/老年人/健康效用Key words
Quality of life/Health status indicators/Aged/Health utility分类
医药卫生引用本文复制引用
武轶群,刘武军,温苏申,胡永华,李凯,刘括,唐迅,曹洋,王晋伟,李娜,刘建江,于立平,许海涛..采用欧洲五维健康量表测量北京郊区老年人健康效用的实证研究[J].北京大学学报（医学版）,2012,44(3):397-402,6.基金项目
国家自然科学基金(30671807,30872173)和国家重点基础研究发展计划(973计划,2006CR503903)项目资助 （30671807,30872173）
