北京大学学报（医学版）2012，Vol.44Issue(3)：444-447,4.DOI:10.3969/j.issn.1671-167X.2012.03.023
铬酸盐接触工人肺通气功能的动态观察
Dynamic observation of pulmonary ventilation function in workers contacting chromate
摘要
Abstract
Objective: To explore changes of pulmonary ventilation function of chromate exposed workers. Methods; Ninety-five chromate exposed workers were used as exposure group, and forty-two workers without chromate exposure as control group. Pulmonary ventilation function was performed two times in the winter of 2010 and 2011 respectively in one chromate manufactured factory in Henan Province. Results; In 2010, pulmonary ventilation function of chromate exposed group compared with the control group, forced vital capacity [ FVC, (75. 38 ± 15. 23)L vs. (83.99 ±26. 52)L] , forced expiratory volume in one second [FEV1,(82. 13 ±16.51 )L vs. (91. 24 ±30. 03 ) L], FEV1/FVC( 112. 10 ± 13.23vs. 116.18 ±11.32), peak expiratory flow [PEF,(74.31 ±28. 09) L/s vs. (78. 13 ±28. 34)L/ s] , maximal expiratory flow [ MEF,( 101.23 ±46.37) I/sis. (110.02 ±41.40)L/s] , maximum ventilation volume [MVV,(90. 82 ±16.89)L/min vs. (99.95 ±22.61 )L/min]were significantly decreased ( P < 0. 05 ). In 2011, pulmonary ventilation function of chromate exposed group compared with the control group, FVC[(72.34±14. 18) L vs. (81.01 ±20. 79) L], FEV1 [(76. 04 ± 16. 20) L vs. (86.71 ± 24.53)L], FEV,/FVC(109.10 ±16. 18 vs. 114.08 ± 10. 79), PEF[ (71.35 ±24. 87 )L/s vs. (75.36± 20.67)L/s], MEF[(96.51±30.17)L/s vs. (107. 11 ±34.81)L/s], MVV[ (84.85 ±21.22)L/min vs. (96.77 ±22.63)L/min] were also significantly decreased(P <0. 05). 2011 compared with 2010, pulmonary ventilation function of chromate exposed group FEV, [ (76. 04 + 16. 20) L us. ( 82. 13 ± 16.51 )L], MEF[(96.51 ±30. 17)L/s us. (101.23 ±46.37)L/s], MVV[(84.85 ±21. 22) L/min vs. (90. 82 ± 16. 89) L/min] were significantly decreased(P <0. 05). Comparing the classification and category of pulmonary dysfunction based on FVC, FEV, , FVC/ FEV,, no difference was found for classification between the two groups and the category of pulmonary dysfunction almost belongs to limit type, which did not change with exposed time. Conclusion; Chronic chromate exposure can cause significant effects on pulmonary function of the workers, and the types of work in production can affect the results.关键词
铬酸盐类/肺通气/职业病Key words
Chromates/Pulmonary ventilation/Occupational diseases分类
医药卫生引用本文复制引用
巴特,王云,李雨铮,贾光,顾永恩,余善法,程广超,王晶,陈田,宋艳双,杨敬林,钱琴..铬酸盐接触工人肺通气功能的动态观察[J].北京大学学报（医学版）,2012,44(3):444-447,4.基金项目
卫生部部属(管)医院临床学科重点项目([2007]35346)和首都医学发展基金(2007-1006)资助 （管）
