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多肿瘤标志物蛋白芯片检测中铁蛋白在恶性肿瘤中的诊断价值

李毅 许明芳 顾咸庆 汪广杰 杨宇馨 廖玲 周芊 王东

重庆医学2012,Vol.41Issue(19):1920-1922,1925,4.
重庆医学2012,Vol.41Issue(19):1920-1922,1925,4.DOI:10.3969/j.issn.1671-8348.2012.19.009

多肿瘤标志物蛋白芯片检测中铁蛋白在恶性肿瘤中的诊断价值

Clinical significance of serum ferritin within multiple tumor markers for diagnosis of malignancy

李毅 1许明芳 1顾咸庆 1汪广杰 1杨宇馨 1廖玲 1周芊 1王东1

作者信息

  • 1. 第三军医大学大坪医院野战外科研究所肿瘤中心,重庆,400042
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摘要

Abstract

Objective To investigate the clinical significance of serum ferritin within multiple tumor markers for diagnosis of malignancy. Methods The measurement results of serum ferritin collected from 25 076 cases were analyzed. The positive rates of serum ferritin in malignant tumor patients, benign disease patients and health examinations were compared, and combination with other tumor markers of protein chip were further analyzed. Results The positive rate of serum ferritin in patients with malignant tumors was significantly higher than in benign disease patients and health examinations(P<0. 01). The positive rate of serum fer-ritin in pancreatic cancer was highest(28. 9%). The most common positive tumor marker accompanied with serum ferritin was CA125(46. 2%),followed by CEA(34. 0%) and CA19-9(29. 4%). Conclusion The positive serum ferritin combined with other tumor markers of protein chip may help to improve the diagnosis of malignancy.

关键词

肿瘤标志物/多肿瘤标志物蛋白芯片/铁蛋白质类/诊断

Key words

tumor marker/multiple tumor marker protein chip/ferritins/diagnosis

引用本文复制引用

李毅,许明芳,顾咸庆,汪广杰,杨宇馨,廖玲,周芊,王东..多肿瘤标志物蛋白芯片检测中铁蛋白在恶性肿瘤中的诊断价值[J].重庆医学,2012,41(19):1920-1922,1925,4.

重庆医学

OA北大核心CSCDCSTPCD

1671-8348

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