重庆医学2012，Vol.41Issue(20)：2012-2014,3.DOI:10.3969/j.issn.1671-8348.2012.20.002
新疆昌吉维吾尔族17个Y-STR基因座遗传多态性
Genetic polymorphisms of seventeen Y-chromosomeal STR loci in XinJiang Changji Uygur Population
摘要
Abstract
Objective To investigate the allelic and haplotype frequency distribution of seventeen short tandem repeat loci of Y chromosome in Xinjiang Uygur population in Changji. Methods Seventeen Y-STR loci of which the template DNAs were extracted from blood samples of 154 unrelated male individuals in Uygur population, were amplified by using the AmpFlSTR YfilerTM. The PCR products were analyzed and genotyped with ABI3130XL Sequencer. Results The gene diversity ranged from 0. 529 7 to 0. 959 9 at DYS456,DYS389 I ,DYS390,DYS389 II ,DYS458,DYS19 ,DYS385a/b,DYS393,DYS391 ,DYS439 ,DYS635 ,DYS392, Y-G∧T∧-H4,DYS4 37,DYS438, and DYS448. A total of 151 different haplotypes were observed. The haplotype diversity value calculated from all 17 loci was 0. 999 7. Conclusion The 17th Y-STR loci in Xinjiang Uygur population in Changji are highly affluent genetic polymorphic and can offer valuable genetic datas for paternity testing and paternal genetic lineages evolution.关键词
Y染色体/STR/维吾尔族/遗传多态性Key words
Y chromosome/ short tandem repeat/ Uygur/ genetic polymorphism引用本文复制引用
张丽萍,陈健刚,蒲红伟,付志敏,杨昊..新疆昌吉维吾尔族17个Y-STR基因座遗传多态性[J].重庆医学,2012,41(20):2012-2014,3.基金项目
国家自然科学基金资助项目(30960134). （30960134）
