重庆医学2012，Vol.41Issue(20)：2027-2028,2031,3.DOI:10.3969/j.issn.1671-8348.2012.20.008
原发性甲状旁腺功能亢进症85例临床及病理分析
Clinical and pathological analysis of primary hyperparathyroidism in 85 cases
左庆瑶 1刘宝岳 2邓丽丽1
作者信息
- 1. 北京积水潭医院内分泌科,100035
- 2. 北京积水潭医院病理科,100035
- 折叠
摘要
Abstract
Objective To explore the clinical manifestations, diagnosis and pathology diagnosis of primary hyperparathyroidism (PHPT). Methods A retrospective study of 85 consecutive patients with PHPT was performed. Results Among the 85 cases, including 25 males and 60 females,the age ranged from 12 to 72 (average 36. 0±13. 2) years. The clinical manifestations were various. Misdiagnosis rate was 81. 2%(69/85). The diagnostic sensitivity of 99Tcm-MIBI was 95. 4% (62/65) , ultrasound 80. 0% (60/ 75)and CT 63. 0% (34/54) , respectively. 81 patients were with pathologically proven parathyroid adenomas, 1 case with hyperplasia and 3 cases with carcinomas. Among the 3 cases with parathyroid carcinomas,the levels of serum calcium in 2 cases were above median and 1 case was with parathyroid crisis. 1 case with parathyroid carcinomas was diagnosed as atypical adenomas 4 years ago. Conclusion The screening for PHPT in patients with bone pains,osteoporosis and urinary calculi is recommended. 99Tcm-MIBI is preferred for the localization and with the combination of 99Tcm-MIBI,B ultrasound and CT may improve the diagnostic accuracy of PHPT. Our data supports watchful follow up for atypical parathyroid adenomas because of the risk of recurrence and malignancy.关键词
甲状旁腺功能亢进,原发性/甲状旁腺肿瘤/非典型腺瘤/诊断Key words
:hyperparathyroidism,primary/parathyroid neoplasm/atypical parathyroid adenoma/diagnosis引用本文复制引用
左庆瑶,刘宝岳,邓丽丽..原发性甲状旁腺功能亢进症85例临床及病理分析[J].重庆医学,2012,41(20):2027-2028,2031,3.
