电化学2012，Vol.18Issue(3)：229-234,6.
阵列纳米通道中氨基官能团质子化研究
Protonization of Amino Functional Groups Confined in Nanochannels
摘要
Abstract
Protonization process is the key step of acid-base reaction and occurs in many biological processes. Study of the protonization process of molecules and/or functional groups in confined conditions would assist un- derstanding in the acid-base theory and confinement effect of biomolecules. In this paper, we developed a novel approach to study protonization of functional groups in porous anodic alumina array nanochannels by measuring the flux of electrochemical active probes using an Au film electrochemical detector sputtered at the end of the nanochannels. The protonization status of the surface functional groups in nanochannels can change the surface charges and further modulate the transportation of charged electroactive probes through nanochannels. The titra- tion curve for the protoniation of amine groups in nanochannel confined condition is obtained by measuring the current signal of ferricyanide probe flowing through an anino-anchored PAA nanochannel array at different solu- tion pH. Results show that the protonization of amino group in nanochannel occurs in one step with a pKl/2 = 5.9. The present method provides an effective tool to study the protonization processes of various functional groups and biomoelcuels.关键词
多孔氧化铝模板/质子化/等电点/限域效应/电化学分析Key words
porous anodic alumina/protonization/isoelectric point/confinement effect/electrochemical anal- ysis分类
化学化工引用本文复制引用
高红丽,周凯琳,王琛,李素娟,章慧,夏兴华..阵列纳米通道中氨基官能团质子化研究[J].电化学,2012,18(3):229-234,6.基金项目
国家973计划项目 （）
国家自然科学基金项目 （）
高等学校博士点基金项目 （）
江苏省自然科学基金攀登计划项目（No.BK2010009）资助 （）
