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军团菌肺炎患儿血清铁蛋白水平变化及意义

李长振 饶菁菁 黄永国 王蓉 孙红 艾洪武

广东医学2012,Vol.33Issue(11):1571-1573,3.
广东医学2012,Vol.33Issue(11):1571-1573,3.

军团菌肺炎患儿血清铁蛋白水平变化及意义

The significance of the serum ferritin in Legionella pneumonia in children

李长振 1饶菁菁 1黄永国 1王蓉 1孙红 1艾洪武1

作者信息

  • 1. 湖北省武汉市妇女儿童医疗保健中心检验科,430016
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摘要

Abstract

Objective To investigate the role of serum ferritin in Legionella pneumonia in children. Methods Seventy - nine children with confirmed Legionella pneumonia were analyzed retrospectively. The hospitalized children with bacterial pneumonia, viral pneumonia, mycoplasma pneumonia and tumor in the same period were enrolled as controls. The serum ferritin levels before and after treatments were assessed by chemiluminescence. Results The serum ferritin level in Legionella pneumonia group was ( 1 589. 2 ±254. 8 ) ng/mL before treatment, while it was ( 867. 9 ± 62. 7 ) ng/ mL in tumor group; and they were significantly higher than those in the other control groups ( P <0. 05 ). The ferritin levels in bacterial pneumonia group and viral pneumonia group were normal, while was slightly increased in some cases in mycoplasma pneumonia group. Significant reduction of ferritin was revealed in Legionella pneumonia group after treatments, and furthermore significantly more prominent than those in the control groups ( P < 0. 01 ), in which there was no significant reduction after treatment. Conclusion The elevated serum ferritin strongly suggests the diagnosis of Legionella pneumonia in children, especially when it is 5 ~6 times over the normal level. Furthermore, it can be applied in prognosis prediction of treatment.

关键词

军团菌肺炎/支原体肺炎/血清铁蛋白/巨噬细胞

Key words

Legionella pneumonia/ mycoplasma pneumonia/ serum ferritin/ macrophages

引用本文复制引用

李长振,饶菁菁,黄永国,王蓉,孙红,艾洪武..军团菌肺炎患儿血清铁蛋白水平变化及意义[J].广东医学,2012,33(11):1571-1573,3.

广东医学

OA北大核心CSCDCSTPCD

1001-9448

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