国际医药卫生导报2012，Vol.18Issue(10)：1487-1489,3.DOI:10.3760/cma.j.issn.1007-1245.2012.10.052
神经节苷脂联合大剂量免疫球蛋白治疗中重度新生儿缺氧缺血性脑病的临床研究
C1inical research of thetherapy of ganglioside combined with high-dose immunoglobulin for neonate with hypoxic-ischemic encephalopathy
摘要
Abstract
Objective To investigate the clinical effect of ganglioside with high-dose immunoglobulin therapy treating on severe neonatal hypoxic-ischemic encephalopathy.Methods 80 severe hypoxic-ischemic encephalopathy neonate were selected and randomly divided into experimental group(42 cases) and control group(38 cases).Control group received conventional treatment,while experimental group received ganglioside with high-dose immunoglobulin therapy.Followed up 1 ～ 2 months,then compared recovery time and neonatal behavioral neurological assessment of two groups.Results The neurological symptoms after treatment,recovery time and NBNA scores of two groups had significant differences(P ＜ 0.05),and the curative effect of experimental group was better than that of control group.Gonclusion The application of ganglioside with high-dose immunoglobulin therapy treating on neonatal hypoxic-ischemic encephalopathy can effectively shorten the course of treatment.关键词
神经节苷脂/免疫球蛋白/中重度/缺氧缺血性脑病Key words
Ganglioside/Immunoglobulin/Moderately severe/Hypoxic-ischemic/Encephalopathy引用本文复制引用
冯少敏..神经节苷脂联合大剂量免疫球蛋白治疗中重度新生儿缺氧缺血性脑病的临床研究[J].国际医药卫生导报,2012,18(10):1487-1489,3.
