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1578例大肠息肉的病理类型与癌变因素探讨

杜小娟

河北医学2012,Vol.18Issue(10):1356-1360,5.
河北医学2012,Vol.18Issue(10):1356-1360,5.DOI:10.3969/j.issn.1006-6233.2012.10.003

1578例大肠息肉的病理类型与癌变因素探讨

The Pathological Type and Carcinogenesis Factors on 1578 Cases of Colorectal Polyp

杜小娟1

作者信息

  • 1. 中国人民解放军第五医院消化内科,宁夏,银川,750004
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摘要

Abstract

Objective: To investigate the various pathological types of colorectal polyps and carcinogene-sis-related factors. Method: 1578 cases of colorectal polyps detected by colonoscopy in our hospital from January 2002 to December 2011 , reviewing the incidence of colorectal polyps, age, location, size, shape, and the pathological type of carcinogenesis factors. Result: Colon polyp detection rate was 22.72% , carci-nogenesis rate was 5. 64% ; A significant difference of different age groups are detected ( X = 8. 250, P = 0.016 ), with a high detection of middle-aged patients. Colorectal polyps occurred in common in the rectum (32.00% ) and sigmoid colon ( 35. 80% ), with polyp diameter ≤ lcm ( 78. 90% ). Adenomatous polyps was the highest proportion in the diameter of lcm—2cm polyps ( 70. 12% ). Morphological studies found non— lobulated polyps were more common ( 80. 04% ). It was found in carcinogenesis factors that elderly patients ( X2= 10.070 P = 0.002 ), occurrence in the rectum and sigmoid colon ( X2 = 0. 843 P = 0. 016 ), polyp diameter> 2cm ( X2 = 114. 173, P <0. 001 ), lobulated polyps ( X2 = 16.66, P <0. 001 ), adenomatous polyposis coli (X = 71. 14 p = <0.001) increased carcinogenesis rate significantly compared with other factors. Conclusion: The incidence of colorectal polyps are closely related to the age and sex; Different pathological types of colorectal polyps had significantly different clinical features ; Occurrence in the rectum and sigmoid colon, non - lobulated, adenomatous polyposis coli diameter > 2.0cm are risk factors of carcinogenesis ; Colorectal polyps is timely to treat, regular follow-up and therefore reducing the incidence of colorectal cancer.

关键词

大肠息肉/病理/癌变

Key words

Colorectal polyps/Pathology/Carcinogenesis

引用本文复制引用

杜小娟..1578例大肠息肉的病理类型与癌变因素探讨[J].河北医学,2012,18(10):1356-1360,5.

河北医学

OACSTPCD

1006-6233

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