胃癌组织中β-连环蛋白、基质金属蛋白酶-7的表达及意义OACSTPCD
Significance and expression of β-catenin and MMP-7 in gastric carcinoma
目的:探讨β-连环蛋白(β-catenin)、基质金属蛋白酶-7(MMP-7)在胃癌组织中的表达及相互关系.方法:应用免疫组织化学ABC法检测胃癌组织、胃黏膜组织中β-连环蛋白表达;应用蛋白质印迹法检测β-连环蛋白阳性组胃癌组织中MMP-7蛋白表达.结果:75例胃癌组织中有35例β-连环蛋白呈阳性表达,阳性率为46.67%;30例胃黏膜组织中仅有3例β-连环蛋白呈阳性表达,阳性率为10.00%,差异有统计学意义(P<0.05).低分化胃癌组…查看全部>>
Objective; To study expression of β-catenin, MMP-7 and its significance in patients with gas-tric carcinoma. Methods: The expression of β-catenin in 75 tissue of gastric carcinoma was detected by im -munohistochemistry ABC method , and the expriession of MMP -7 in the positive tissue of β-eatenin in gastric carcinoma was detected by Western blot. Results; The protein of β-catenin was expressed in 35 of 75 cases in gastric carcinoma, the positive percentage…查看全部>>
吕成方;赵远;王永忠
常州市奔牛人民医院内科,江苏,常州,213131江苏大学临床医学院,江苏,镇江,212001镇江市第一人民医院外科,江苏,镇江,212002
医药卫生
胃癌β-连环蛋白基质金属蛋白酶-7蛋白质印迹
gastric carcinoma β-eatenin matrix metalloproteinase-7 Western blot
《江苏大学学报（医学版）》 2012 (4)
346-349,4
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