淫羊藿苷对去势雌性大鼠骨质疏松的影响OACSTPCD
Effect of icariin on osteoporosis in ovariectomized female rats
目的 研究淫羊藿苷对去势雌性大鼠骨质疏松的影响,为开发传统中药治疗骨质疏松症提供理论依据.方法 将60只3月龄健康雌性Wistar大鼠随机分为空白对照组(SHAM组,20只),去势造模组(OVX组,20只),淫羊藿苷组(ICA组,20只).模型建立后ICA组大鼠给予淫羊藿苷(浓度30mg/ml,10ml/kg,1次/d)灌胃90d.处死所有大鼠前采用股动脉取血法采集大鼠血液测定血清雌二醇水平、血碱性磷酸酶(ALP)和抗酒石酸酸性磷酸酶5b(TRA…查看全部>>
Objective To provide the theoretical evidence for the development of Traditional Chinese Medicine in treatment of osteoporosis by studying the effect of icariin(ICA) on osteoporosis in ovariectomized female rats. Methods Sixty healthy female Wistar rats at the age of 3 months were randomly divided into control group(sham group), ovariectomized group(OVX group) and ICA group(20 in each group). After a model was established, rats in ICA group received lOml/kg …查看全部>>
宋渊;李盛华;何志军;张亚维;周明旺
天津中医药大学,天津300193甘肃省中医院,甘肃兰州730050天津中医药大学,天津300193甘肃省中医院,甘肃兰州730050甘肃省中医院,甘肃兰州730050
特种医学
淫羊藿苷去势骨组织骨质疏松
icariin castration bone tissue osteoporosis
《军医进修学院学报》 2012 (4)
400-403,4
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