军医进修学院学报2012，Vol.33Issue(5)：470-472,515,4.
远端型溃疡性结肠炎临床特点及复方血竭灌肠疗效分析
Clinical characteristics of distal ulcerative colitis and therapeutic effect of compound dracorhodin enema on it
张月凡 1李楠 2张林 2翟俊山 2吴凯 2王艳梅2
作者信息
- 1. 解放军总医院/军医进修学院,北京100853
- 2. 解放军第309医院消化内科,北京100091
- 折叠
摘要
Abstract
Objective To study the clinical characteristics of distal ulcerative colitis(DUC) and assess the therapeutic effect of compound dracorhodin enema on it. Methods Clinical characteristics of DUC, ulcerative pancolitis(PUC) and Crohn's disease(CD) were analyzed by comparing their clinical, endoscopic and pathological findings. One hundred and twenty-eight DUC patients were divided into experimental group and control group. Patients in experimental group were treated with oral mesalazine and compound dracorhodin enema while those in control group were given 0.9% sodium chloride injection. Therapeutic effects of the two treatment modalities on DUC were compared. Results The clinical manifestations of DUC included diarrhea, rectal tenesmus, mucous bloody stool and its main pathological manifestation was crypt abscess, which were similar to those of UPC(P>0.05) but significantly different from those of CD(P<0.05). The total effective rate of 5-week therapy was significantly higher in experimental group than in control group. No significant difference was observed in the improvement of diarrhea, abdominal pain, rectal tenesmus, and mucous bloody stool between the two treatment modalities(P>0.05). However, the effect of compound dracorhodin enema was obviously better on mucous bloody stool and its side effects were less in experimental group than in control group(P>0.05). Conclusion DUC is characterized by certain typical clinical symptoms due to its occurring site. Compound dracorhodin enema is a safe and effective procedure for it and worthy of application in clinical practice.关键词
结肠炎,溃疡性/复方血竭灌肠/远端型溃疡性结肠炎Key words
colitis, ulcerative/ compound dracorhodin enema/ distal ulcerative colitis分类
临床医学引用本文复制引用
张月凡,李楠,张林,翟俊山,吴凯,王艳梅..远端型溃疡性结肠炎临床特点及复方血竭灌肠疗效分析[J].军医进修学院学报,2012,33(5):470-472,515,4.
