临床口腔医学杂志2012，Vol.28Issue(4)：195-198,4.DOI:10.3969/j.issn.1003-1634.2012.04.001
血管再生治疗犬年轻恒牙根尖周炎的实验研究
Experiments on treatment of apical periodontitis with pulp revascularization in immature dog teeth
摘要
Abstract
Objective: To compare effects of revascularization and apexification on treatment of apical periodontitis in immature dog premolar teeth. Method: Thirty immature premolar teeth from 3 dogs aged approximately 5-6 months were infected. and randomized into one control group and two experimental groups with ten teeth each. All teeth were radiographed after 4 weeks. 8 weeks and 12 weeks respectively, for comparison of the root continuing development.The animals were euthanized 12 weeks later, then sections were prepared routinely and the degree of hard tissue formation was evaluated histomorphically. Result: 1.X-ray: Apical closure was found in three groups. The percentage of apical closure of experimental groups was better than that of control group (P < 0.05) , while there were no statistical differences between experimental groups (P > 0.05) .2.Histomorphical observation:Thickening of the cannal walls and elongation of the root in revascularization group and control group due to the apposition of newly generated cementum-like tissue termed herein in-tracanal cementum (IC) .and moreover, bone-like tissue was observed in the canal space in two groups and was termed in-tracanal bone (IB). There were statistical differences between revascularization group and control group in the percentage of IC and IB (P < 0.05) .In apexification group, IB and IC were no found.Conclusion: The ability of wall thickening and root e-longation of pulp revascularization was better than that of apexification.关键词
年轻恒牙/根尖周炎/血管再生/根尖诱导成形术Key words
immature teeth/ apical periodontitis/ revascularization/ apexification分类
医药卫生引用本文复制引用
张蕾,刘英群,王锐,吕晶,薛欣,施磊..血管再生治疗犬年轻恒牙根尖周炎的实验研究[J].临床口腔医学杂志,2012,28(4):195-198,4.基金项目
哈尔滨医科大学第一临床医学院科研基金项目(Y08-002) （Y08-002）
