临床输血与检验2012,Vol.14Issue(2):135-137,3.DOI:10.3969/j.issn.1671-2587.2012.02.013
血清TGAb、TPOAb在甲状腺疾病中的应用价值
The Value of Serum TGAb and TPOAb Detection in Thyroid Diseases
朱梅 1陶存武 1许建宁 1李迎霞1
作者信息
- 1. 230061 合肥,安徽医科大学第三附属医院,合肥市第一人民医院核医学科
- 折叠
摘要
Abstract
To investigate the changes of thyroglobulin antibody (TGAb) and thyroid peroxidase antibody (TPOAb) in patients with hyperthyroidism and hypothyroidism, and evaluate its clinical value. Methods 100 cases with hyperthyroidism were divided into four groups: newly diagnosed hyperthyroidism group,hyperthyroidism relapse group. remission of hyperthyroidism and hypothyroidism after treatment groups. Serum levels of TGAb and TPOAb were detected in 100 hyperthyroidism, 60 hypothyroidism cases and 30 healthy adults. Results The positive rates of TGAb and TPOAb in patients with hyperthyroidism and hypothyroidism were higher than those of normal control group. The TPOAb-positive rates in pre-therapy and post-treatment were significantly higher than that of TGAb in 100 patients with hyperthyroidism patients in pretherapy and post-treatment. No matter newly diagnosed hyperthyroidism group,hyperthyroidism relapse group, remission of hyperthyroidism group, hyperthyroidism after treatment group, the two antibody positive rates were different significantly between pretherapy and post-treatment. Conclusion Quantitative detection of TGAb and TPOAb are significant in identification, diagnosis and treatment of thyroid disease. Clinical value of TPOAb is higher relatively than TGAb.关键词
甲状腺球蛋白抗体/甲状腺过氧化物酶抗体/甲状腺功能亢进/甲状腺功能减退Key words
Thyroglobulin antibody Thyroid peroxidaseantibody Hyperthyroidism Hypothyroidism分类
医药卫生引用本文复制引用
朱梅,陶存武,许建宁,李迎霞..血清TGAb、TPOAb在甲状腺疾病中的应用价值[J].临床输血与检验,2012,14(2):135-137,3.