临床误诊误治2012，Vol.25Issue(4)：39-41,3.DOI:10.3969/j.issn.1002-3429.2012.04.021
舒张早期心肌负向峰值速度阶差对左室舒张功能的评估价值
Assessment of Left Ventricular Diastolic Function by Peak Negative Myocardial Velocity Gradient
摘要
Abstract
Objective To assess the significance of peak negative myocardial velocity gradient ( NPMVG) in early diastole as an indicator of left ventricular (LV) diastolic function. Methods NPMVG was obtained from M-mode tissue Doppler imaging ( TDI) and was compared with mitral flow velocity indices in 69 subjects: 14 normal subjects, 30 patients with hypertensive heart disease (HHD) , and 25 patients with dilated cardiomyopathy (DCM). In a subgroup of 56 patients, effects of preload increase on these indices in 40 patients were assessed by passive leg lifting. In the 13 patients with congestive heart failure, the measurements were repeated after 23 ± 15 days of volume-reducing therapy. Results NPMVG was significantly depressed both in HHD and DCM (P<0. 05). In contrast, transmittal flow indices distinguished HHD from normal, but failed to distinguish DCM from normal. Transmittal flow velocity indices were significantly altered (P<0. 05), while NPMVG remained unchanged by leg lifting (P >0.05). Volume-reducing therapy resulted in apparent worsening of the transmittal flow velocity pattern, both E and E/A were depressed, DCT increased; while NPMVG improved after the therapy (P<0. 05). Conclusion NPMVG derived from TDI may be a noninvasive indicator of LV diastolic function that is less affected by preload alterations than the transmittal flow velocity indices, and can be used for efficacy evaluation and the follow-up of the patients.关键词
心脏病/超声检查,多普勒,彩色/心室功能,左Key words
Heart disease/ Ultrasonograph, doppler, colored/ Ventricular function, left分类
医药卫生引用本文复制引用
王菲,王冬梅,张徽,曹士考,张春东,刘皎然,田庆波..舒张早期心肌负向峰值速度阶差对左室舒张功能的评估价值[J].临床误诊误治,2012,25(4):39-41,3.基金项目
河北省重大科技项目(11276124D) （11276124D）
