临床眼科杂志2012，Vol.20Issue(3)：254-256,3.DOI:10.3969/j.issn.1006-8422.2012.03.024
青光眼小梁切除术联合羊膜移植的临床应用
Trabeculectomy combined with amniotic membrane transplantation for glaucoma
张俊峰 1李林 2李俊1
作者信息
- 1. 519000珠海,暨南大学医学院第三附属医院珠海市人民医院眼科
- 2. 广州市番禺区中心医院眼科
- 折叠
摘要
Abstract
Objective To compare outcomes of trabeculectomy combined with mitomyein C (MMC) and amniotic membrane transplantation (AMT) with those of trabeculectomy with MMC alone in glaucoma. Methods This prospective randomized clinical trial included 58 eyes with glaucoma. Trabeculectomy with MMC and single-layer AMT under die scler-al flap was performed in 29 eyes (study group) and trabeculectomy with MMC alone in 29 eyes (control group). The outcome measures included intraocular pressure (IOP) and appearance of the bleb were compared and complication between the two groups. All patients were followed for 12 months. Results The difference of the mean postoperative intraocular pressure was statistically significant in the control group and in the study group at 12 months follow-up ( P <0.05). IOP decreased from 37.4 ±6.3 mm Hg and 35.6 ±8.4 mm Hg pteoperatively to 16.4 ±5.0 mm Hg and 14.7 ±3.6 mm Hg postoperative respectively. However, there was no IOP difference between the two groups postoperatively at 12 months( P =0.143). Success rates of the study group (IOP≤21 mm Hg or with glaucoma medications) is 93.1%, And the control group is 82.8% , There were not significant difference among the two groups( P =0.420). Promote forming functiona filtering bleb in the study group (89.7% ) is more than in the control group (65.5%), the difference was statistically significant ( P =0.028). Postoperative shallow anterior chamber e study group incidence (13.8% ) was significantly lower than the control group (37.9% ), the difference was statistically significant ( P = 0.036). Conclusion Trabeculectomy combined with MMC and AMT has higher success rates is worth further clinical popularization and application.关键词
青光眼/小梁切除术/羊膜移植Key words
Glaucoma/ Compound trabeculectomy/ Amniotic membrane transplantation引用本文复制引用
张俊峰,李林,李俊..青光眼小梁切除术联合羊膜移植的临床应用[J].临床眼科杂志,2012,20(3):254-256,3.
