老年医学与保健2012，Vol.18Issue(2)：94-98,5.DOI:10.3969/j.issn.1008-8296.2012-02-10
华北地区门诊血糖控制不佳患者用药情况调查分析
Survey analysis on application of drugs in the out-patients with unsatisfactory blood glucose in north China
贾鹤晋 1李春霖 1龚燕平 1刘维 2谢云 3柳洁 4苏胜偶 5刘博伟6
作者信息
- 1. 100853 北京市,解放军总医院南楼内分泌科
- 2. 300052 天津市,天津总医院内分泌科
- 3. 300070 天津市,天津医科大学代谢病医院
- 4. 030012 山西太原,山西省人民医院内分泌科
- 5. 050051 河北石家庄,北医科大学第二医院内分泌科
- 6. 066000 河北秦皇岛,秦皇岛人民医院内分泌科
- 折叠
摘要
Abstract
Objective To analyze the application of hypoglycemic drugs in out-patients with unsatisfactory blood glucose in north China to provide rational references for drug using. Methods The information of out-patients with unsatisfactory blood glucose, including general conditions, blood glucose level, the use of hypoglycemic drugs and hypoglycemia event happened in recent 3 months were collected from December 2006 and March 2007 through clinic interviews. By clinic interviews, questionnaires, physical examinations, laboratory tests and past history review, in multi-centers of 15 hospitals in north China. Statistical analyses were performed to elucidate the current situation of medications for DM in two groups; the older group and the young and middle-aged group. Results Along with the prolongation of the course of DM, most patients have to be controlled their blood glucose by drug combination. Metformin was the most frequently used medicine (the older group 45.7%, the young and middle-aged group53.0%) either in single drug prescription or drug combination; With respect to the maximum-dose or over-dose issue, sulfonylurea was used with highest dose (the older group 73.5%, the young and middle-aged group 81.2 %); With respect to the drug combination, metformin plus sulfonylurea combinations was the most frequently used pattern (the older group 22.8%, the young and middle-aged group 42.6%). As for the side effects of treatment, sulfonylurea was the medicine that most frequently lead to hypoglycemia (the older group 55.6%, the young and middle-aged group 64.3%). Conclusions In North China, a large proportion of the patients controlled their blood glucose by lifestyle or one kind of medicine. Single drug therapy or drug combination therapy protocol is relatively too late. In some cases, some medicines were used in a too high dosage which increased the frequency of hypoglycemia during treatment.关键词
糖尿病/血糖控制/用药方式/剂量Key words
Diabetes mellitus/ Blood glucose control/ Drug use way/ Dose分类
医药卫生引用本文复制引用
贾鹤晋,李春霖,龚燕平,刘维,谢云,柳洁,苏胜偶,刘博伟..华北地区门诊血糖控制不佳患者用药情况调查分析[J].老年医学与保健,2012,18(2):94-98,5.
