四川医学2012，Vol.33Issue(5)：853-855,3.
恩替卡韦治疗乙型肝炎肝硬化短期疗效分析
Efficacy of entecavir treat patients with chronic hepatitis B and cirrhosis
倪扬 1钟刚2
作者信息
- 1. 新津县人民医院消化内科,四川新津611430
- 2. 双流县第二人民医院消化内科,四川双流610213
- 折叠
摘要
Abstract
To investigate the effectacy of entecavir in the treatment of patients with chronic hepatitis B and cirrhosis. Methods We retrospectively analyzed 126 cases who had treat hepatitis B and cirrhosis in our department from September 2009 to February 2011. The 126 cases were randomly divided into 2 groups of 67 cases in the control group that were given treatment entecavir and 59 case in experimental that were given lamivudine. Contrast the convertion rate of HBV-DNA after 6 weeks, 12 weeks,24 weeks, TBil,AST, ALT, Cllild-Pugh. Results ①The convertion rate of HBV-DNA after 6 weeks, 12 weeks, 24 weeks were significant differences of two groups (P < 0. 05). ②The level of TBil, HBV-DNA were significant differences of two groups(P <0.05). ③Child-Pugh were higher in the post-treatment than pretherapy in groups (P <0.05) and were significant differences of two groups (P < 0.05). Conclusion Short term use entecavir is effective in treatment of patients with chronic hepatitis B and cirhosis.关键词
恩替卡韦/拉米夫定/乙型肝炎/肝硬化Key words
entecavir/lamivudine/hepatitis B/liver cirrhosis分类
医药卫生引用本文复制引用
倪扬,钟刚..恩替卡韦治疗乙型肝炎肝硬化短期疗效分析[J].四川医学,2012,33(5):853-855,3.
