高效液相色谱-串联质谱法同时检测化妆品中6种禁用着色剂OA北大核心CSCDCSTPCD
Simultaneous determination of 6 forbidden colorants in cosmetics by high performance liquid chromatographytandem mass spectrometry
建立了高效液相色谱-串联质谱(HPLC-MS/MS)同时测定膏状和粉状化妆品中苏丹红Ⅳ、酸性紫49、苏丹蓝2、溶剂红49、碱性紫l和颜料橙5等6种禁用着色剂的检测方法.样品经乙醇-乙腈(3:2,v/v)超声振荡提取20min、离心净化及氮吹浓缩后,在Luna C18色谱柱(150mm×2.1mm,5μm)上进行反相液相色谱分离,以甲醇和10 mmol/L乙酸铵溶液为流动相进行梯度洗脱采用多反应监测(MRM)模式进行质谱测定.根据保留时间及质谱图上…查看全部>>
A method of high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) has been established for the simultaneous determination of six forbidden colorants including Sudan IV, Acid Violet 49, Sudan Blue 2, Solvent Red 49, Basic Violet 1 and Pigment Orange 5 in cream and powdery matrix cosmetics. The samples were extracted with ethanol-acetonitrile (3:2, v/v) solution by ultrasonic technique for 20 min, then centrifuged for purification and en…查看全部>>
林维宣;孙兴权;赵雪蓉;徐伟;郭桂媛
辽宁出入境检验检疫局技术中心,辽宁 大连 116001辽宁出入境检验检疫局技术中心,辽宁 大连 116001辽宁出入境检验检疫局技术中心,辽宁 大连 116001辽宁出入境检验检疫局技术中心,辽宁 大连 116001大连工业大学生物与食品工程学院,辽宁 大连 116034
化学化工
高效液相色谱-串联质谱禁用着色剂化妆品
high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) forbidden colorant cosmetics
《色谱》 2012 (5)
527-532,6
国家质量监督检验检疫总局立项课题(课题号:2009IK-149).
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