生物骨科材料与临床研究2012，Vol.9Issue(2)：14-18,后插4,6.DOI:10.3969/j.issn.1672-5972.2012.02.004
可吸收腰椎间融合器的生物力学研究
Research of biomechanical changes of lumbar absorbable design fusion cage
徐峰 1膝海军 2蔡贤华 1范丽静2
作者信息
- 1. 广州军区武汉总医院骨科,湖北武汉430070
- 2. 山东潍坊第89医院脊柱外科二区,山东潍坊261012
- 折叠
摘要
Abstract
Objective To develop a new Lumbar Absorbable Design Fusion Cage made of absorbable material Poly-DL-lactic Acid ( PDLLA) and put it into animal to observe its biomechanical changes. Method The LADFC was implanted into intervertebral disc and were tested by axial compressive testing and torsional testing at 12w, 24w and 36w. Result At 12w, vertebral bodies implanted with LADFC were stronger than Control Group (P0.05 ) in compressive testing ; at 24w the stiffness of Experimental Group was decreased significantly (P<0.05 ) , while Control Group increased not significantly >.P>0.05 ) but were still stronger than Control Group (P<0.05 ) ; at 36w the stiffness of Experimental Group was decreased not significantly (P>0.05 ) and were similar with Control Group (P>0.05 ) . At 12w, vertebral bodies implanted with LADFC were stronger than Control Group (P<0.01) in torsional testing; at 24w the stiffness ofExperimentalGroupwasdecreasedsigrnificantly(P<0.01 ), while Control Group increased not significantly (F>0.05 ) butofExperimenlalGroupwerestillstrongerthanControlGroup(P<0.01 ) ; at 36w the softness of Experimental Group was decreased not sigmificantly (P>0.05 ) and were similar with Control Group (P>0.05 ) . Conclusion In the process of fusion, the mechanical strength of LADFC made of PDLLA gradually declined, however the lumbar fusion cage mnintains the mechanical strength before it fuses with the bone firmly. Thus the process ensures the realization of the fusion of bone graft, at the same time, lumbar fusion cage is degraded and absorbed finally and there is no stress to affect the growth of bone which was certain positive meaning.关键词
腰椎间融合器/可吸收材料/生物力学Key words
Interbody fusion/ Biodegradable material/ Biomechanical Changes分类
医药卫生引用本文复制引用
徐峰,膝海军,蔡贤华,范丽静..可吸收腰椎间融合器的生物力学研究[J].生物骨科材料与临床研究,2012,9(2):14-18,后插4,6.
