S-腺苷蛋氨酸和谷胱甘肽联产发酵中盐胁迫的作用OACSCDCSTPCD
Co-production of S-adenosylmethionine and glutathione under salt-stress by Candida utilis
摇瓶条件下考察不同的盐(NaCl,Na2SO4,KCI,K2SO4)胁迫对产朊假丝酵母发酵联产S-腺苷蛋氨酸(SAM)和谷胱甘肽(GSH)的影响.结果发现适当浓度的Na+和K+对SAM和GSH合成具有部分促进作用,而Cl-的作用则相反.以Na2 SO4为代表,考察分批发酵条件下盐胁迫的作用,结果表明:在酵母细胞生长后期(15 h)添加10 g/L Na2SO4,SAM、GSH以及二者的最大联产量为252.5、285.9和521.9 mg/L,比对…查看全部>>
Effects of salt stress of NaCl, Na2SO4, KC1 and K2SO4 on co-production of S-adenosylmethi-onine(SAM) and glutathione (GSH) was investigated in flaske by Candida utilis CCTCC M 209298. It was shown that Na + and K + enhanced the co-production of SAM and GSH on appropriate concentrations, while C1- inhibited cell growth and product biosynthesis. Based on the results, salt stress resulted from Na2SO4 was further studied under batch cultivation. The concen…查看全部>>
王玉磊;叶子优;贺秋萍;王文龙;卫功元
苏州大学 基础医学与生物科学学院,苏州215123苏州大学 基础医学与生物科学学院,苏州215123苏州大学 基础医学与生物科学学院,苏州215123苏州大学 基础医学与生物科学学院,苏州215123苏州大学 基础医学与生物科学学院,苏州215123
生物科学
S-腺苷蛋氨酸联产发酵谷胱甘肽盐胁迫
S-adenosylmethionine co-production glutathione salt-stress
《生物加工过程》 2012 (3)
33-38,6
苏州大学大学生课外学术科研基金项目(KY2011094A)
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