生物信息学2012，Vol.10Issue(2)：116-119,4.DOI:10.3969/j.issn.1672-5565.2012.02.11
SNP与基因检测及表达中的RCA技术
RCA Technology in SNP and gene detection and expression
张江峰 1曾照芳1
作者信息
- 1. 重庆医科大学检验医学院,临床检验诊断学教育部重点实验室,重庆400016
- 折叠
摘要
Abstract
Rolling circle amplification (RCA) is a new molecular biology detection method. Not only will this directly to the highly specific detection of nucleic acids, but also by linear or exponential amplification for the signal cascade, with its sensitivity up to one copy of the nucleic acids molecules. Thus, it can be used in detection of rare molecular. At present, RCA is mainly used in fields of whole genome DNA detection, sequencing, single nucleo-tide polymorphism, DNA microarray and protein microarray analysis etc.关键词
滚环扩增/核酸测序/单核苷酸多态性/芯片Key words
Rolling circle amplification/ Sequencing f Single nucleotide polymorphism/ Microarray分类
生物科学引用本文复制引用
张江峰,曾照芳..SNP与基因检测及表达中的RCA技术[J].生物信息学,2012,10(2):116-119,4.
