山西大学学报（自然科学版）2012，Vol.35Issue(2)：285-292,8.
植物铁蛋白结构、性质及其在纳米材料制备中的应用
Structure, Function of Phytoferritin and its Application in Nano Material Science
摘要
Abstract
Ferritins are a broad superfamily of iron storage proteins,present in all living organisms and play important roles in controlling cellar iron homeostasis. To date, relatively little information is available on structure and function of phytoferritin compared to animal ferritin. Phytoferritin is observed in amyloplast whereas animal ferritins are largely found in the cytoplasm of cell. In contrast to animal ferritin,phytofer-ritins exhibit two major distinctive features in structure: (1)phytoferritin contains a specific extension pep-tide (EP) at the N-terminal while animal ferritin lacks. The EP is located on the exterior surface of protein,which recently has been found to act as a second ferroxidase center for iron-binding and oxidation,and regulate iron release during the germination and early growth of seedlings. (2) only H-type subunit has been identified in phytoferritin which is usually a heteropolymer consisting of two different subunits, H-l and H-2,sharing ~80℅ amino acid sequence identity. These two subunits in phytoferritin play a positively cooperative role in iron oxidative deposition in protein. The obtained ferritin has attracted great interest among researchers in the field of nanodevices due to its specific structure. Biomineralization of ferritin core has been extended to the artificial synthesis of homo-geneousmetal complex nanoparticles and semiconductor nanoparticles. The inner cavity of apophytoferritin is an ideal spatially restricted chemical reaction chamber for nanoparticles synthesis. This review focuses on recent progresses in structure,function of phytoferritin and its application in nano material science.关键词
植物铁蛋白/EP肽段/H-1/H-2/纳米颗粒Key words
phytoferritin/EP domain/ H-l and H-2 subunits /nanoparticles分类
生物科学引用本文复制引用
赵广华,云少君..植物铁蛋白结构、性质及其在纳米材料制备中的应用[J].山西大学学报（自然科学版）,2012,35(2):285-292,8.基金项目
国家自然科学基金(30972045) （30972045）
