实用妇产科杂志2012,Vol.28Issue(4):282-284,3.
500例妊娠期肝内胆汁淤积症围生结局分析
Perinatal Outcomes of Intrahepatic Cholestasis of Pregnancy: Analysis of 500 Cases
何丽 1罗丹 1刘毅 1胡丽娜2
作者信息
- 1. 四川省成都市妇女儿童中心医院,四川成都610091
- 2. 重庆医科大学附属第二医院,重庆400010
- 折叠
摘要
Abstract
Objective:To study the perinatal outcomes of intrahepatic cholestasis of pregnancy(ICP). Methods:The clinical data of 500 women with mild and severe ICP from Jan 2007 to Jan 2011 were retrospectively analyzed and 300 normal cases were as the control group, Perinatal outcomes were observed. Results:①126 cases were diagnosed as severe ICP while 374 cases were as mild ICP. The average gesta-tional weeks of trie study groups and control group were 35.1 ± 1.2, 37.4 ± 1. 6 and 39. 2 ± 1.9. The premature delivery rates were 96.4%, 16.6% and4.1%. There was statistical differences(P<0.05). ②me-conium-stained amnionic fluid, fetal distress and neonatal asphyxia rates in the severe ICP group was higher than the mild ICP group. ③ cases of perinatal mortality were found, which belonged to severe ICP cases. Conclusions graduation diagnosis and treatment of ICP is helpful to improve perinatal prognosis.
关键词
妊娠期肝内胆汁淤积症/妊娠结局/胎儿窘迫/羊水粪染/新生儿窒息Key words
Intrahepatic cholestasis of pregnancy/Perinatal outcome/Fetal distress/Meconium-stained amniotic fluid/Neonatal asphyxia分类
医药卫生引用本文复制引用
何丽,罗丹,刘毅,胡丽娜..500例妊娠期肝内胆汁淤积症围生结局分析[J].实用妇产科杂志,2012,28(4):282-284,3.