天然产物研究与开发2012，Vol.24Issue(5)：605-609,5.
壳寡糖螯合铬对糖尿病小鼠降血糖作用的研究
Hypoglycemic Effects of Chitooligosaccharide-chromium (Ⅲ)Complex on Diabetic Mice
曲婉秋 1唐晓琳 1王秀武1
作者信息
- 1. 辽宁师范大学生命科学学院,大连116029
- 折叠
摘要
Abstract
To study the effects of chitooligosaccharide-chromium( III ) complex(Cos-Cr)on diabetic mice. Selecting ten male mice as the normal control group. Thirty diabetes mice were randomly divided into 3 groups, diabetes control group (n = 10),Cos group (n = 10), Cos-Cr group (n = 10). The mice were dissected after 4 weeks, determinations of serum glucose concentration. Cos-Cr can significantly decrease fasting blood glucose level, increase body weight as well as index spleen. Symptoms of hunger and thirsty were improved obviously in diabetic mice. Cos-Cr has protective effects on alloxan-induced hepatic injury in mice. Hepatocytes lesion was alleviated markedly. Cos-Cr can decrease blood glucose concentration and improve diabetic symptoms in mice.
关键词
壳寡糖螯合铬/四氧嘧啶/糖尿病/血糖/肝脏/脾脏Key words
chitooligosaccharide-chromium (III) /alloxan/diabetic/blood glucose/liver/spleen分类
医药卫生引用本文复制引用
曲婉秋,唐晓琳,王秀武..壳寡糖螯合铬对糖尿病小鼠降血糖作用的研究[J].天然产物研究与开发,2012,24(5):605-609,5.
