武汉工程大学学报2012，Vol.34Issue(5)：13-15,3.DOI:10.3969/j.issn.1674-2869.2012.05.004
双(3,5-二甲基苯基)膦的合成
Preparation of bis (3,5-dimethylphenyl) phosphine
申永存 1李倩 1夏定 1陈世坤1
作者信息
- 1. 武汉理工大学化工学院,湖北武汉430070
- 折叠
摘要
Abstract
Bis(3 ,5-dimethyl phenyl)phosphine is an effective ligand for asymmetric synthesis of S-metolachlor and there is no commercial product in domestic at present. In order to promote the development of asymmetric synthesis process of S-metolach)or, the synthetic process was studied in this paper. With bis (3 ,5-dimethyl phenyl)phosphine oxide as raw material, bis(3,5-dimethyl phenyl)phosphine was synthesized by deoxidization through diisobutyl aluminium hydride,and the optimal conditions were the ration of bis(3 ,5-dimethyl phenyl) phosphine oxide to diisobutyl aluminum hydridemole of 1:3,reaction temperature of 65 t, reaction time of 1 h, and the production rate of 89% . The results show that this method is simple, and easy to control with less side reactions.关键词
膦配体/二异丁基氢化铝/还原Key words
phosphorus ligands/ DIBAL/ deoxidized分类
化学化工引用本文复制引用
申永存,李倩,夏定,陈世坤..双(3,5-二甲基苯基)膦的合成[J].武汉工程大学学报,2012,34(5):13-15,3.
