无机材料学报2012，Vol.27Issue(6)：655-659,5.DOI:10.3724/SP.J.1077.2012.00655
头孢拉定/蒙脱石插层化合物的制备
Preparation of Cefradine/Montmorillonite Intercalation Compound
赵彦钊 1郭文姬 1王兰2
作者信息
- 1. 陕西科技大学材料科学与工程学院,西安710021
- 2. 陕西科技大学生命科学与工程学院,西安710021
- 折叠
摘要
Abstract
The cefradine/montmorillonite compounds were prepared by pharmaceutical montmorillonite (MMT) and sodium-montmorillonite (Na-MMT) by the method of solution intercalation. The drug load was quantitatively measured by UV spectrophotometry. The structures of compounds were determined by X-Ray Diffraction (XRD) and Fourier transformed infrared (FT-IR) spectroscope. The results show that cefradine can be intercalated into MMT mainly due to ion exchange, which cannot intercalate into MMT by mechanically mixing. Pharmaceutical MMT shows better ion exchange property after sodium modification, which is easily intercalated. The basal spacing of pharmaceutical MMT changes little after intercalation in water, however, the basal spacing of Na-MMT and pharmaceutical MMT after sodium modification increase.关键词
蒙脱石/头孢拉定/离子交换性/溶液插层法Key words
montmorillonite/ cefradine/ ion exchange/ solution intercalation分类
化学化工引用本文复制引用
赵彦钊,郭文姬,王兰..头孢拉定/蒙脱石插层化合物的制备[J].无机材料学报,2012,27(6):655-659,5.
