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难治性精神病的立体定向多靶点联合损毁治疗

孙平安 白万胜 黎柏源 应敬国 周波 高云 文雅 薛红丽

西北国防医学杂志2012,Vol.33Issue(2):142-144,3.
西北国防医学杂志2012,Vol.33Issue(2):142-144,3.

难治性精神病的立体定向多靶点联合损毁治疗

Treatment of intractable schizophrenia by stereotactic multi-target radiofrequency ablation

孙平安 1白万胜 1黎柏源 1应敬国 1周波 1高云 1文雅 1薛红丽1

作者信息

  • 1. 解放军323医院神经外科,陕西西安710054
  • 折叠

摘要

Abstract

Objective: To evaluate the efficacy of intracranial stereotactic multi -target radiofrequency ablation for the treatment of intractable schizophrenia. Methods; Intracranial multiple nuclei including amygdala, mcdialis septal area, cingulate gyrus and so on were located by stereotactic technique with computed tomography, microelec-trode and electric impedance and treated by radiofrequency ablation in 160 patients with intractable schizophrenia. The therapeutic effect was estimated with psychiatric rating scale 6 months after treatment. Results; Based on clinical global impression (CGI) , 84 patients were obviously improved, 70 were improved and 6 were invalid. There were significant differences in the brief psychiatric rating scale ( BPRS) between preoperative data and postoperative data ( P < 0.05), Conclusion; The stereotactic multi - target radiofrequency ablation might be an effective method for the treatment of intractable schizophrenia.

关键词

精神分裂症/立体定向/射频毁损

Key words

Schizophrenia/ Stereotactic technique/ Radiofrequency ablation

分类

医药卫生

引用本文复制引用

孙平安,白万胜,黎柏源,应敬国,周波,高云,文雅,薛红丽..难治性精神病的立体定向多靶点联合损毁治疗[J].西北国防医学杂志,2012,33(2):142-144,3.

西北国防医学杂志

OACSTPCD

1007-8622

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