中国组织工程研究2012，Vol.16Issue(28)：5165-5169,5.DOI:10.3969/j.issn.2095-4344.2012.28.008
低功率激光修复末端病大鼠跟腱胶原
Low level laser for repair of collagen in the tendon of rats with enthesiopathy
摘要
Abstract
BACKGROUND: Low level laser therapy (LLLT) has the specific stimulation effect on organism (photobiomodulation). In general case, it can produce some biological effects without temperature increase. OBJECTIVE: To observed the effect of low level laser on contents of hydroxyproline and gene expression of collagen I in the tendon of rats with enthesiopathy. METHODS: Ninety-six male Wistar rats were randomly divided into two groups. The control group was without ant treatment. Rats in the model group were stimulated to the feet with electrostimulating jumping method to build the model of enthesiopathy. Rats in the LLLT group were treated with LLLT to the tendon after model building. RESULTS AND CONCLUSION: Compared with the control group, the contents of hydroxyproline and gene expression of collagen I in the tendon of rats with enthesiopathy were significantly decreased (P < 0.05). After LLLT, low level laser could increase the contents of hydroxyproline and gene expression of collagen I in the tendon of rats with enthesiopathy, and this started from 7 days and was obviously increased at 14 days. It is indicated that low level laser can improve the contents of hydroxyproline and the metabolism of collagen I in the tendon of rats with enthesiopathy, and can promote the healing of tendon in early stage.关键词
低功率激光/末端病/跟腱/羟脯氨酸/Ⅰ型胶原mRNA分类
医药卫生引用本文复制引用
沈勇伟,史晓伟..低功率激光修复末端病大鼠跟腱胶原[J].中国组织工程研究,2012,16(28):5165-5169,5.基金项目
江苏省社会发展项目(BS2006020),课题名称:运动训练预防跟腱损伤的研究. （BS2006020）
