中国组织工程研究2012，Vol.16Issue(29)：5460-5464,5.DOI:10.3969/j.issn.2095-4344.2012.29.029
无机载银抗菌剂在口腔修复中的研究应用现状
Research status of inorganic silver-carrying antibacterial agent in oral prosthodontics
摘要
Abstract
BACKGROUND: Oral environment is bacterial, and so the effects of restorative treatments face challenges from micro-organisms. To some extent, the success of treatment depends on the antimicrobial properties of restorative material. The silver antibacterial agent has become a research hotspot for its characteristics of broad spectrum antimicrobial, high biological security and rare drug tolerance. OBJECTIVE: To review the application and research of inorganic silver-carrying antibacterial agent in prosthodontics material and provide a theoretical basis for the further clinical application. METHODS: CNKI, PubMed and OVID databases were retrieved online for articles concerning the application of inorganic silver-carrying antibacterial agent in oral prosthodontics from 1990-01 to 2011-04. Articles highly related to the application and research of inorganic silver-carrying antibacterial agent in oral prosthodontics that published recently or in the authorized journals were included. Twenty-nine articles were included in result analysis. RESUTS AND CONCLUSION: Silver is an effective antibacterial material and has a good effect on oral common pathogenic bacteria, such as candita albicans, streptococcus mutans and lactobacillus. Application of silver into prosthodontics material has a broad prospect. However, silver ion is unstable and tarnished easily. In the modification study of prosthodontics material, it is needed to further research for overcoming oxidizing discoloration, reducing the affection of silver on material physical and chemical properties, as well as the clinical application and evaluation of prosthodontics material.关键词
银/无机抗菌剂/抗菌机制/修复/生物材料分类
医药卫生引用本文复制引用
李庆艳,郑新颖,吕俏,林华,高宁..无机载银抗菌剂在口腔修复中的研究应用现状[J].中国组织工程研究,2012,16(29):5460-5464,5.基金项目
四川省科技厅支持项目(2008SG0023). （2008SG0023）
