中国组织工程研究2012，Vol.16Issue(29)：5489-5492,4.DOI:10.3969/j.issn.2095-4344.2012.29.035
新型带电荷硫酸钙/β-磷酸三钙复合骨水泥经单、双侧椎弓根注入椎体成形:渗漏及填充椎体的力学特征
New charged calcium sulfate/beta-tricalcium phosphate compound bone cement for unilateral and bilateral transpedicular vertebroplasty: Bone cement leakage and biomechanics changes
秦毅 1江建明 2朱青安 1瞿东滨 1杨勇 1刘鹏1
作者信息
- 1. 南方医科大学南方医院脊柱外科,广东省广州市,501515
- 2. 广东省中医院珠海医院骨伤二科,广东省珠海市,519020
- 折叠
摘要
Abstract
BACKGROUND: A new type of charged calcium sulfate/beta-tricalcium phosphate compound bone cement can restore vertebral mechanical properties, and meanwhile reduce the risk for bone cement leakage in traditional vertebroplasty and improve operation safety.
OBJECTIVE: To study bone cement leakage and vertebral biomechanical changes by observation of the new charged calcium sulfate/beta-tricalcium phosphate compound bone cement in unilateral and bilateral transpedicular vertebroplasty.
METHODS: Osteoporotic thoracolumbar specimens selected from eight old male corpses were used to prepare a vertebral compression fracture model. Two successive vertebral specimens were paired to be cross-assigned into unilateral and bilateral groups. In the unilateral group, 4 mL of new charged calcium sulfate/beta-tricalcium phosphate compound bone cement was applied in unilateral transpedicular vertebroplasty; 4 mL of new charged calcium sulfate/beta-tricalcium phosphate compound bone cement was used for bilateral transpedicular vertebroplasty in the bilateral group, 2 mL at each side.
RESULTS AND CONCLUSION: The leakage volume of bone cement in the unilateral group was significantly higher than that in the bilateral group (P < 0.05). There was no significant difference in the maximum load and stiffness between the two groups (P > 0.05). Bilateral transpedicular vertebroplasty with new charged calcium sulfate/beta-tricalcium phosphate compound bone cement is better, and the decreased volume of injected bone cement helps to reduce the leakage risk of bone cement. However, there is no difference between the vertebral biomechanical changed of the two groups.关键词
硫酸钙/β-磷酸三钙/椎体成形/骨水泥/渗漏/刚度/生物材料分类
医药卫生引用本文复制引用
秦毅,江建明,朱青安,瞿东滨,杨勇,刘鹏..新型带电荷硫酸钙/β-磷酸三钙复合骨水泥经单、双侧椎弓根注入椎体成形:渗漏及填充椎体的力学特征[J].中国组织工程研究,2012,16(29):5489-5492,4.
