中国组织工程研究2012，Vol.16Issue(31)：5737-5741,5.DOI:10.3969/j.issn.2095-4344.2012.31.009
移植肾穿刺20例活组织病理检查的临床价值
Percutaneous biopsy of renal allograft: Analysis of pathological and clinical value in 20 cases
裴向克 1韩永 2王强 2许亮 3郭晖 2石炳毅 3蔡明2
作者信息
- 1. 解放军第281医院泌尿外科,河北省秦皇岛市,066100
- 2. 解放军第309医院全军器官移植中心,北京市,100091
- 3. 华中科技大学同济医学院附属同济医院器官移植研究所,湖北省武汉市,430030
- 折叠
摘要
Abstract
BACKGROUND: To determine the cause of graft renal dysfunction after renal transplantation based on the clinical manifestations, non-invasive examinations and clinical experience is often in trouble, percutaneous renal biopsy can provide important evidence-based theory.
OBJECTIVE: To investigate the clinical significance of renal allograft biopsy.
METHODS: Pathological data of 20 patients with renal allograft biopsy and the clinical outcome of accordingly adjusted treatment were retrospectively analyzed.
RESULTS AND CONCLUSION: Acute rejection occurred in seven cases (35.0%), doubtful acute rejection occurred in two cases (10.0%), doubtful acute rejection combined drug poisoning occurred in one cases (5.0%), drug poisoning occurred in three cases (15.0%), chronic allograft nephropathy occurred in three cases (15.0 %), no obvious abnormality occurred in three cases (15.0%), acute renal tubular necrosis occurred in one case (5.0%). After therapeutic regimen was adjusted, graft function of nine cases (45%) returned to normal, seven cases (35%) improved, three cases (15%) did not change markedly and one case (5%) deteriorated slightly. Renal graft biopsy is important for the etiological diagnosis of the graft function deterioration after kidney transplantation and is in favor of the adjustment of the therapeutic regimen.关键词
肾移植/肾穿刺/病理诊断/肾功能异常/急性排斥反应分类
医药卫生引用本文复制引用
裴向克,韩永,王强,许亮,郭晖,石炳毅,蔡明..移植肾穿刺20例活组织病理检查的临床价值[J].中国组织工程研究,2012,16(31):5737-5741,5.
