畜牧兽医学报2012，Vol.43Issue(5)：816-820,5.
芩连液与白虎汤对气分证家兔补体经典途径活化的影响比较
Effect of Baihu Soup and Qinlian Liquid on the Classical Pathway of Complement Activation in Rabbit with Qifen Syndrome
摘要
Abstract
The objective of this study was to compare the curative effect of Baihu Soup with Qinlian Liquid in molecular angle. The animal model of Qifen Syndrome was found through intravenous (i. v. ) injection of LPS, and the model was treated with Baihu Soup and Qinlian Liquid respectively. Before and after treatment, the expression changes of serum CH50, C3 and CRP gene in liver tissue were determined by ELISA and real-time quantitative PCR respectively. The results demonstrated that complement system was activated through classical pathway. Baihu Soup can cured the animals through make genes of C3 and CRP high expression, and Qinlian Liquid plays a certain role only through up-regulated the gene expression of CRP. The curative effect of Baihu Soup on animal Qifen Syndrome is superior to that of Qinlian Liquid.关键词
气分证/补体/CH50/C3/CRPKey words
Qifen Syndrome/ complement/ CH50/ C3/ CRP分类
农业科技引用本文复制引用
张世栋,王东升,王旭荣,李世宏,李锦宇,陈炅然,李宏胜,严作廷..芩连液与白虎汤对气分证家兔补体经典途径活化的影响比较[J].畜牧兽医学报,2012,43(5):816-820,5.基金项目
“十一五”国家科技支撑计划重点课题(2008BADB4B01-2) （2008BADB4B01-2）
