西南国防医药2012，Vol.55Issue(7)：762-764,3.DOI:10.3969/j.issn.1004 - 0188.2012.07.025
直肠癌经术中髂内动脉预置泵化疗109例报告
Clinical study of chemotherapy via intraoperative preset pump in internal iliac artery on rectal cancer(report of 109 cases)
陈焕新 1鲁瑞林 1郑乃国 2梅伟1
作者信息
- 1. 629000,四川,遂宁,四川省遂宁市第一人民医院外二科
- 2. 第三军医大学西南医院普外科
- 折叠
摘要
Abstract
Objective To investigate the effective ways of chemotherapy on rectal cancer. Methods A retrospective analysis of clinical data was made among 109 cases receiving chemotherapy via preset pump in internal iliac artery( IIA )from March 1993 to November 2008. Among these cases,63 ones were male,and 46 ones were female. Thirty three ones were in the Dukes Stage B;65 ones in stage C;5 in stage D;6 ones had recurrent cancer. Administration for the first time was in d 7 - 14 after the operation,and 30 d was a treatment circle. The chemotherapy was completed after 5 or 6 circles. Results Follow up was made in 52 - 181 months. The whole course of treatment was successfully done in 107 cases. Local reaction occurred in 36 cases, which included odynuria, perineal distending pain and "map - like" piebald changes or mild pain,pruritus,and blister on the gluteal skin near the part of pump insertion. Most symptoms were recovered in short term. The general reaction of gastrointestinal reactions such as nausea and diarrhia occurred in 106 cases,which mostly were mild and relieved after the conventional treatment. Their WBC generally decreased,but was not less than 2. 0 × 109/L. Conclusion Compared with the systemic vein chemotherapy, this remedy has advantages as below:( 1 )lower side effect and comparatively milder symptoms such as nausea, vomiting, and decrease of WBC, etc; ( 2 ) convenient, safe, and practical manipulation and repeatedly usable procedure;( 3 )good local therapeutic efficacy.关键词
直肠癌/化疗/髂内动脉泵Key words
rectal cancer/ chemotherapy/ pump in internal iliac artery
分类
医药卫生引用本文复制引用
陈焕新,鲁瑞林,郑乃国,梅伟..直肠癌经术中髂内动脉预置泵化疗109例报告[J].西南国防医药,2012,55(7):762-764,3.
