中国医疗设备2012,Vol.27Issue(4):55-59,11,6.DOI:10.3969/j.issn.1674-1633.2012.04.017
形态测量学在阿尔茨海默病和轻度认知障碍的早期诊断及病程转化预测的应用研究
Research on the Disease-diagnosis and Conversion-prediction in the Patients with MCI and Mild AD based on Multi-morphometry
摘要
Abstract
With the rising incidence of Alzheimer's disease and mild cognitive impairment, but there is no effective way to prevention or treatment. Morphometry can get the quantitative information of the whole brain structure comprehensively and objectively. Morphology methods which help to Disease-diagnosis and Conversion-prediction in the Patients with MCI and mild AD have got wide attentions. Morphometry main includes Voxel-Based Morphometry (VBM), Deformation-Based Morphometry (DBM) and Tenor-Based Morphometry (TBM). With the development of imaging technology, the morphometry technologies, especially the VBM, made some progress in MCI and AD diagnosis and transformation forecast, but there are many of issues should be further study to resolve them.关键词
阿尔茨海默病/轻度认知障碍/基于体素的形态学测量方法/基于张量的形态测量学/基于形变的形态测量学Key words
alzheimer's disease/ mild cognitive impairment/ voxel-based morphometry/ tenor-based morphometry/ deformation-based morphometry分类
社会科学引用本文复制引用
夏翃,刘卫芳,胡玲静,杨慧芳,刘苏,童隆正..形态测量学在阿尔茨海默病和轻度认知障碍的早期诊断及病程转化预测的应用研究[J].中国医疗设备,2012,27(4):55-59,11,6.基金项目
国家自然科学基金(81071128) (81071128)