中国当代儿科杂志2012，Vol.14Issue(4)：247-252,6.
早期蛋白质和能量摄入对早产儿生长影响的研究
Effect of early protein and energy intake on the growth of premature infants
韩露艳 1王丹华1
作者信息
- 1. 中国医学科学院北京协和医学院北京协和医院儿科,北京100730
- 折叠
摘要
Abstract
Objective To study the effect of early protein and energy intake on early growth velocity of premature infants. Methods Clinical data on premature infants with a birth weight of less than 1800 g were collected retrospectively, including records of general status, enteral and parenteral nutrition and growth parameters. These premature infants were divided into two groups according to the timing of amino acid administration: early supplementation (the first 24 hre of life; EAA group; n = 112) and late supplementation (after 24 hrs of life; LAA group; n = 52). Protein and energy intake, protein/energy ratio and growth velocity during hospital stay were compared between the two groups. Correlation analysis was used to evaluate the association of early protein and energy intake and protein/energy ratio with growth velocity of infants. Results Compared with the LAA group,the EAA group presented lower weight loss (6.3% vs 8. 8% ) , shorter time to return to birth weight (7 days vs 9 days), and higher head circumference growth (0.79 ±0.25 cm/week vs0.55 ± 0.25 cm/week) and weight growth velocity(20 ±3 g/kg · d vs 17 ±3 g/kg · d) (P <0.05). The correlation analysis indicated that protein and energy intake and protein/energy ratio on the 3rd and 7th days of life were positively correlated with weight growth velocity. The protein and energy intake per week after returning to birth weight was positively correlated with weight growth velocity (r = 0. 709, P <0. 01 ). Significant correlations were found between the protein and energy intake and both head circumference and length growth velocity on the 3rd and the 7th days of life. Conclusions Early administration of amino acids can reduce weight loss, shorten the time taken to return to birth weight, and increase weight and head circumference growth velocity in premature infants. An appropriate increase in protein intake can improve weight, circumference and length growth velocity.关键词
营养/蛋白质/能量/生长速率/早产儿Key words
Nutrition/ Protein/ Energy/ Growth velocity/ Premature infant分类
医药卫生引用本文复制引用
韩露艳,王丹华..早期蛋白质和能量摄入对早产儿生长影响的研究[J].中国当代儿科杂志,2012,14(4):247-252,6.
