中国动脉硬化杂志2012，Vol.20Issue(6)：552-556,5.
原发性高血压患者血浆同型半胱氨酸水平与脉搏波传导速度的相关性
Correlation Analysis of Homocysteine and Pulse Wave Velocity in Essential Hypertensive Patients
石蕊 1姜铁民 2赵季红 2董彦 2李东霞 2李玉明2
作者信息
- 1. 天津医科大学研究生院,天津市300070
- 2. 武警后勤学院附属医院心内科,天津市300162
- 折叠
摘要
Abstract
Aim To investigate the association of plasma homocysteine (Hey) with arterial stiffness, measured as brachial-ankle pulse wave velocity (BaPWV) in essential hypertensive patients. Methods 146 essential hypertensive patients were enrolled in the study. All the patients accepted physical examination, laboratorial checks, and coronary risk factors were recorded. They were classified into four groups according to interquartile interval of homocysteine. And they were also classified into two groups according to BaPWV. The differences among these groups were analyzed. Results The linear correlation analysis showed that Hey was more positively correlated with age, 3moking, systolic blood pressure (SBP), pulse pressure (PP), puke pressure index (PFI) and BaPWV (r=0.278, 0.272, 0.608, 0.575, 0.460 and 0.351, P <0.05). BaPWV was more positively correlated with Hey, SBP, PP and PPI (r =0.351, 0.322, 0.322 and0.253, P<0.01). Multiple logistic regression analysis showed that PP and Hey were both independent risk factors for BaPWV. Conclusion This study showed a positive correlation between high levels of plasma Hey and arterial stiffness measured as BaPWV in essential hypertensive patients.关键词
原发性高血压/同型半胱氨酸/臂踝脉搏波传导速度Key words
Essential Hypertension/Homocysteine/Brachial- Ankle Pulse Wave Velocity分类
医药卫生引用本文复制引用
石蕊,姜铁民,赵季红,董彦,李东霞,李玉明..原发性高血压患者血浆同型半胱氨酸水平与脉搏波传导速度的相关性[J].中国动脉硬化杂志,2012,20(6):552-556,5.
