中国临床心理学杂志2012，Vol.20Issue(3)：363-366,4.
针刺疗法改善美沙酮维持治疗门诊患者抑郁和焦虑症状疗效和安全性
Acupuncture Therapy for Depressive and Anxious Symptoms of Outpatients Receiving Methadone Maintenance Treatment: A Randomized Controlled Trial
李毅 1钟宝亮 1黄卓玮 1刘伟 1张尧 1刘学兵 1郝伟2
作者信息
- 1. 华中科技大学同济医学院附属精神卫生中心,湖北 武汉 430022
- 2. 中南大学湘雅二医院精神卫生研究所,湖南 长沙 410011
- 折叠
摘要
Abstract
Objective: To examine the efficacy and safety of acupuncture therapy for depressive and anxious symptoms of outpatients receiving methadone maintenance treatment (MMT). Methods: By using randomized double-blinded controlled design, eighty-nine MMT outpatients with obvious depressive and anxious symptoms, were randomly assigned to acupuncture group (n=48) and placebo—acupuncture group (n=41). All patients continued their previous MMT schemes. In acupuncture group, acupuncture was applied to Neiguan, Hegu, Zusanli, Sanyinjiao, etc. In placebo-acupuncture group, acupuncture was applied to non-acupoint spots (S mm lateral to the acupoints selected in acupuncture group) with shallow needling technique. The treatment lasted for 8 weeks, 5 sessions per week. For efficacy assessment, patients were administered SAS and SDS at baseline and every two-week interval. Adverse event rates were compared between two groups to assess the safety. Results: Repealed measurement variance analysis revealed that the overall SDS and SAS reduction of acupuncture group was significantly higher than placebo-acupuncture group (F=5.99, P=0.005; f=8.36, P<0.001). The adverse event rates of acupuncture were 8.33% (4/48) and 9.76% (4/41) for acupuncture group and placebo-acupuncture group, their difference was not statistically significant (X2=0.055, P=0.815). Conclusion: Acupuncture therapy can effectively and safely improve the depressive and anxious symptoms of outpatients receiving MMT.关键词
针刺/美沙酮维持治疗/抑郁/焦虑Key words
Acupuncture/ Methadone maintenance treatment/ Depression/ Anxiety分类
医药卫生引用本文复制引用
李毅,钟宝亮,黄卓玮,刘伟,张尧,刘学兵,郝伟..针刺疗法改善美沙酮维持治疗门诊患者抑郁和焦虑症状疗效和安全性[J].中国临床心理学杂志,2012,20(3):363-366,4.
