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疏血通与丹参对脑梗死患者及其高危人群血液流变学影响的Meta分析

颜陶 周岐新 费慧芝 胡小娅 杨秋珺

中国临床药理学与治疗学2012,Vol.17Issue(3):302-307,6.
中国临床药理学与治疗学2012,Vol.17Issue(3):302-307,6.

疏血通与丹参对脑梗死患者及其高危人群血液流变学影响的Meta分析

A Meta-analysis for hemorrheologic parameters in patients with cerebral infarction or high risk population treated by Shuxuetong or Danshen

颜陶 1周岐新 1费慧芝 1胡小娅 1杨秋珺1

作者信息

  • 1. 重庆医科大学药学院药理学教研室,重庆400016
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摘要

Abstract

AIM: To compare effects of Shuxuetong on hemorrheologic parameters to that of Danshen in patients with cerebral infarction or high risk population, so that evidences in Evidence-based Medicine can be provided for clinical pharmacotherapy. METHODS: Thirteen articles corresponding to our researching condition were searched out by retrieving and screening domestic articles from 2000 to 2011 according to the criterion for including or excluding articles. The data were processed by the method of meta-anal-ysis. RESULTS: A comparison between Shuxue-tong versus Danshen:HS [WMD= —0.53, 95%CI (-0.76, -0.31), P<0. 05]; LS [WMD=-1.40, 95%CI (-2.05, -0.74), P <0.05]j PV [WMD=-0.27, 95% CI (-0.39, -0.15), P<0.05], FIB [WMD=-0.75, 95%CI (-0.97, -0.52), P<0.05]; HCT [WMD=-0.05, 95% CI (-0.08, -0.01), P<0.05]. CONCLUSION: The improvement effects of Shuxuetong on hemorrheo-logic parameters are better than that of Dansh-en, even though serious heterogeneity exists a-mong the selected articles.

关键词

疏血通/丹参/血液流变学/脑梗死/高危/Meta分析/循证医学

Key words

Shuxuetong/ Danshen/Hemor-rheology/ Cerebral infarction/ High risk/ Meta-analysis/ Evidence-based medicine

分类

医药卫生

引用本文复制引用

颜陶,周岐新,费慧芝,胡小娅,杨秋珺..疏血通与丹参对脑梗死患者及其高危人群血液流变学影响的Meta分析[J].中国临床药理学与治疗学,2012,17(3):302-307,6.

中国临床药理学与治疗学

OACSCDCSTPCD

1009-2501

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