中国临床药理学杂志2012，Vol.28Issue(6)：406-408,3.
阿托伐他汀对颈动脉粥样硬化患者血浆同型半胱氨酸的影响
The effect of homocysteine of patients with carotid artery atherosclerosis
幸奠霞 1刘先玲 1徐海 1付东伟1
作者信息
- 1. 重庆三峡中心医院老年科,重庆 404000
- 折叠
摘要
Abstract
Objective To observe the effects of atorvastatin calcium on plasma homocysteine of patients with carotid artery atherosclerosis. Methods Ninety - six patients with carotid artery atherosclerosis ware divided into three groups. Patients of group A were given life style guidance and took 100 mg asprin per day as the base treatment Patients of group B took extra 20 mg atorvastatin calcium orally on the basis of group A. In addition to the base treatment of group A, extra 40 mg atorvastatin calcium were taken orally by patients of group C. Hie area of carotid plaque and the level of homocysteine were detected before the treatment and on the 4th, 6th, 8 th week after treatment respectively. Results No significant change was observed in group A and B before and after treatment in area of carotid plaque and the level of homocysteine, which decreased in group C from the 6th to 8th week, and more on the 8th week. Conclusion Taking 40 mg atorvastatin calcium everyday can help to decrease the homocysteine level of patients with carotid artery atherosclerosis, and this effect was parallel to the reduction of carotid plaque area.关键词
阿托伐他汀/同型半胱氨酸/颈动脉粥样硬化Key words
atorvastatin/homocysteine/carotid artery atherosclerosis分类
医药卫生引用本文复制引用
幸奠霞,刘先玲,徐海,付东伟..阿托伐他汀对颈动脉粥样硬化患者血浆同型半胱氨酸的影响[J].中国临床药理学杂志,2012,28(6):406-408,3.
