中国临床药理学杂志2012，Vol.28Issue(6)：429-431,3.
罗哌卡因腰麻对下肢手术患者血流动力学的影响
The haemodynamic effects of ropivacaine on spinal anesthesia for inferior extremity surgery
于琳琳 1王军1
作者信息
- 1. 北京大学第三医院 麻醉科,北京 100191
- 折叠
摘要
Abstract
Objective To compare the haemodynamic effects of equipo-tent doses of ropivacaine and bupivacaine in spinal anaesthesia in adult patients with inferior extremity surgery. Methods Sixty inferior extremity surgery patients with American Society of Anesthesiologists (ASA) I - II were randomly divided into two groups, receiving an intrathecal injection of either 15 mg hyperbaric ropivacaine or 10 mg hypeibaric bupivacaine. Haemodynamic indexes, such as systolic blood pressure(SBP), diastolic blood pressure(DBP) , heart rate( HR) and pulse oxygen saturation ( SpO2) were investigated. Anesthetic effects and side effects were also recorded. Results The anesthetic effects were similar in two groups, which can satisfy the demand of the surgeries. SBP, DBF and HR decreased after the block in both groups. The occurrence rates of hypotension and bradycardia were similar. The values of SpO2 had no significant difference between two groups (P > 0.05). Conclusion Ropivacaine can provide reliable spinal anesthesia without significant haemodynamic advantage, but adverse drug reaction rate less than bupivacaine. 关键词
罗哌卡因/腰麻/血流动力学Key words
ropivacaine/ spinal anaesthesia / haemodynamic effect分类
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于琳琳,王军..罗哌卡因腰麻对下肢手术患者血流动力学的影响[J].中国临床药理学杂志,2012,28(6):429-431,3.
