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白藜芦醇外涂对模拟日光照射所致皮肤红斑的抑制作用

吴严 贾丽丽 郑颖娜 高兴华 陈洪铎 李远宏

中国美容医学2012,Vol.21Issue(5):754-756,3.
中国美容医学2012,Vol.21Issue(5):754-756,3.

白藜芦醇外涂对模拟日光照射所致皮肤红斑的抑制作用

Inhibitive effects of topical resveratrol on skin erythema induced by solar simulator ultraviolet irradiation

吴严 1贾丽丽 2郑颖娜 3高兴华 1陈洪铎 1李远宏1

作者信息

  • 1. 中国医科大学附属一院皮肤科 辽宁沈阳110001
  • 2. 吉林大学附属第四医院皮肤科
  • 3. 河南省人民医院皮肤科
  • 折叠

摘要

Abstract

Objective To investigate the effect of topical resveratrol on skin erythema induced by solar simulator ultraviolet irradiation. Methods Twenty volunteers were recruited and 6 experimental sites were separately marked on their bilateral backs. Sites 1 to 4 were topically applied with resveratrol combination with antioxidant, antioxidant, resveratrol, base, respectively. The products were applied to left-side followed by irradiation, and the products were applied to right-side after irradiation. Sites 5 and site 6 were separatedly designated as positive control and negative control sites. The irradiation last 4 days and skin erythema was observed. Results On the 1st and 2nd days after irradiation, no or only slight erythema were observed on site 1 to site 3. On the 3rd and 4th days, the erythema of site 1 and site 3 remained unchanged comparing to that on the 2nd day, whereas the erythema of site 2 became obvious than before and lighter than that of site 5. The erythema on left-side is slighter than that on right-side. Conclusion Topical resveratol could effectively prevent (more obviously) and reverse the skin erythema induced by solar simulator ultraviolet irradiation.

关键词

白藜芦醇/紫外线/红斑

Key words

resveratol/ultraviolet/erythema

分类

医药卫生

引用本文复制引用

吴严,贾丽丽,郑颖娜,高兴华,陈洪铎,李远宏..白藜芦醇外涂对模拟日光照射所致皮肤红斑的抑制作用[J].中国美容医学,2012,21(5):754-756,3.

基金项目

2010年教育部高等学校博士学科点专项科研基金(课题编号:20102104120007) (课题编号:20102104120007)

中国美容医学

1008-6455

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