中国美容医学2012，Vol.21Issue(5)：778-781,4.
男性型脱发患者头皮雄激素受体表达的研究
Androgen receptor expression in male pattern baldness patients
摘要
Abstract
Objective To investigate AR (androgen receptor)expression in male pattern baldness. Methods Obtain follicles from different scalp areas (occipital area of non-hair loss.hair loss transition and hair loss zone area) of 10 male AGA (androgenetic alopecia) patients and 3 normal scalp. Use immunohistochemistry method to study AR expressions in hair follicles in different regions. Results In the hair follicle bulge and infundibulum,AR expressions in hair loss area and the transitional area are obviously stronger than those in the occipital and the normal control group (P<0.05). In epidermis,AR expressions show no significant difference (P>0.05) in occipital area.hair loss area and the transitional area, but there are significant differences compared to normal control group (P<0.05).ln the sebaceous gland.AR expressions in each group is of no significant difference (P>0.05). Conclusion The AR expressions are different between different regions. In the hair follicle bulge and infundibulum, AR expressions in hair loss area and the transitional area are obviously stronger than those in the occipital, This may be one of the key factors leading to male pattern hair loss.关键词
男性型脱发/雄激素受体Key words
male pattern baldness,androgen receptor分类
医药卫生引用本文复制引用
黄涛,万苗坚,董佳辉,冯智英,谢小元,李英,赖维,计斌..男性型脱发患者头皮雄激素受体表达的研究[J].中国美容医学,2012,21(5):778-781,4.基金项目
广东省自然基金(编号:10151008901000204) （编号:10151008901000204）
中华医学会-欧莱雅基金(编号:H2010040416) （编号:H2010040416）
