中国农业科学2012，Vol.45Issue(6)：1176-1182,7.DOI:10.3864/j.issn.0578-1752.2012.06.016
青山羊表皮生长因子基因表达与毛囊发育特性的研究
Studies on Expression Characteristics of EGF and Development Characteristics of Hair Follicle of Gray Goat
摘要
Abstract
[ Objective] The relationship between the expression of epidermal growth factor and the development of hair follicle was studied. [Method] The histology method, micro-observation approach and QRT-PCR were used to detect the relationship between the expression of EGF and the development of hair follicle of 1-day-old, 1-month-old, 2-month-old, 3-month-old, 4-month-old and 5-month-old lining Gray goat. SAS9.0 was used to analyze the relationship between them. [Result] The resuts indicated that the diameter of primary follicle increased, but not significantly (P>0.05). The diameter of secondary follicle increased very significantly (P<0.0l), The diameter of secondary follicle reached peak of growth at 2-month-old. The expression of EGF increased after birth and achieved the highest at 2-month-old (P<0.01). It decreased extremely significant after 2-month-old (P<0.01). [Conclusion] The primary follicle was completely developed before birth and the secondary follicle was developed after birth. The expression of EGF and the diameter of secondary follicle had a significant positive correlation before 2-month-old (P<0.01). The results indicated that EGF is significantly positive to the development of secondary follicle.关键词
济宁青山羊/毛囊发育/表皮生长因子/定量PCRKey words
Jining Gray goat/hair follicle development/epidermal growth factor/quantitative PCR引用本文复制引用
王睿智,尹逊河,王慧,成子强..青山羊表皮生长因子基因表达与毛囊发育特性的研究[J].中国农业科学,2012,45(6):1176-1182,7.基金项目
国家自然科学基金项目(30671498) （30671498）
