中国全科医学2012，Vol.15Issue(20)：2292-2294,3.DOI:10.3969/j.issn.1007-9572.2012.07.054
2型糖尿病合并脑梗死患者血清超敏C反应蛋白及同型半胱氨酸与颈动脉粥样硬化的关系
Correlation of Serum High-sensitivity C-Reactive Protein and Homocysteine Levels with Carotid Artery Atherosclerosis in Acute Cerebral Infarction Patients with Type 2 Diabetes Mellitus
张敏 1李卫征1
作者信息
- 1. 453000,河南省新乡市中心医院神经内科
- 折叠
摘要
Abstract
To explore the correlation of serum high - sensitivity C - reactive protein ( Hs - CRP ) and homocysteine ( Hey ) with carotid stenosis in patients with acute cerebral infarction with type 2 diabetes mellitus ( DMCI ). Methods Totally 102 acute cerebral infarction patients, including 44 DMCI patients ( DMCI group ) and 58 patients with non - diabetic acute cerebral infarction ( CI group ) were enrolled in this study. The serum hs - CRP and Hey were measured. Carotid artery examination including the inter - media thickness and carotid atheromatous plaque were performed for all patients by the Doppler ultrasonography. Results The serum hs - CRP and homocysteine levels in DMCI group and in CI group showed significant difference ( P < 0. 05 ). The incidence of carotid artery atherosclerosis was 86. 4% in DMCI group and 69. 0% in CI group ( P < 0. 05 ). Inside the DMCI group, the serum levels of hs - CRP and Hey also showed significant differences between patients with unstable/stable plaque and those without plaque; in addition, the serum hs - CRP level in patients with unstable plaque also differed from those with stable plaque ( P < 0. 05 ). Conclusion DMCI patients are more susceptible to carotid artery atheroscle-ros, which may be related with the increased serum hs - CRP and Hey levels.关键词
脑梗死/糖尿病,2型/动脉粥样硬化/超敏/C反应蛋白/同型半胱氨酸Key words
Brain infarction/ Diabetes mellitus, type 2 / Atherosclerosis/ High sensitivity C - reactive protein/ Ho-mocysteine分类
医药卫生引用本文复制引用
张敏,李卫征..2型糖尿病合并脑梗死患者血清超敏C反应蛋白及同型半胱氨酸与颈动脉粥样硬化的关系[J].中国全科医学,2012,15(20):2292-2294,3.
