首页|期刊导航|中国神经再生研究(英文版)|Smoking and Alzheimer's disease among Mongolian and Han Chinese aged 55 years and over living in the Inner Mongolia farming area of China
中国神经再生研究(英文版)2012,Vol.7Issue(20):1570-1577,8.DOI:10.3969/j.issn.1673-5374.2012.20.007
Smoking and Alzheimer's disease among Mongolian and Han Chinese aged 55 years and over living in the Inner Mongolia farming area of China
Smoking and Alzheimer's disease among Mongolian and Han Chinese aged 55 years and over living in the Inner Mongolia farming area of China
摘要
Abstract
Residents aged 55 years or older from 27 communities and two settlements in Xilingol League of Inner Mongolia were selected for participation in an Alzheimer's disease epidemiological investigation from June 2008 to June 2009, including 3 259 Mongolians and 5 887 Han Chinese.The Mongolian subjects in the Alzheimer's disease group were at age of 55 years or older (on average), and more of them were male, illiterate and/or had a history of coronary artery disease and/or diabetes compared with the Mongolian subjects in the non-Alzheimer's disease group. The Han Chinese subjects in the Alzheimer's disease group were at age of 55 years or older (on average) and more of them were women, illiterate and/or had a history of coronary artery disease,and less of them had a history of alcohol consumption compared with the non-Alzheimer's disease group. Non-conditional multivariate stepwise logistic regression identified that male gender,increasing age and having a history of diabetes and/or coronary heart disease were associated with higher odds of Alzheimer's disease among Mongolians while having an educational background was associated with lower odds (OR = 0.259, 95%CI 0.174-0.386). Among the Han Chinese subjects, male gender, increasing age and having a history of coronary heart disease and/or hypertension was associated with higher odds of Alzheimer's disease, while having an educational background was associated lower odds (OR = 0.271, 95%CI 0.192-0.381). The results also indicated that extremely heavy smoking may be a risk factor for Alzheimer's disease in Mongolian males aged over 55 years. There was no significant difference in smoking habits between the Mongolian and Han Chinese subjects with Alzheimer's disease.关键词
Alzheimer's disease/ Mongolian/ Han Chinese population/ elderly/ epidemiology/ risk factor/ protection factorKey words
Alzheimer's disease/ Mongolian/ Han Chinese population/ elderly/ epidemiology/ risk factor/ protection factor引用本文复制引用
Chunyu Zhang,Lin Da,Shigang Zhao,Desheng Wang,Guangming Niu,Huriletemuer..Smoking and Alzheimer's disease among Mongolian and Han Chinese aged 55 years and over living in the Inner Mongolia farming area of China[J].中国神经再生研究(英文版),2012,7(20):1570-1577,8.基金项目
This work was supported by grants from the Science and Technology Research Project at University of Inner Mongolia Autonomous Region,No.NJ09116 ()
Important Project of Inner Mongolia Medical College Affiliated Hospital,No.NYFY ZD 2006001 ()
Social Developmeng of Inner Mongolia Autonomous Region,No.KJT10JHN ()
the Natural Science Foundation of Inner Mongolia Autonomous Region,No.2010MS1121 ()
and the Program of Higher-Level Talents of Inner Mongolia University,No.SPH-IMU,Z00901002. ()