中国比较医学杂志2012，Vol.22Issue(4)：19-22,4.DOI:10.3969/j.issn.1671.7856.2012.04.005
人工哺育期腹泻婴猴奇异变形杆菌的分离与鉴定
Isolation and Identification of Proteus mirabilis from Diarrheic Infant Rhesus Monkeys in the Period of Artificial Feeding
赵远 1杨凤梅 1陈丽雄 1禹文海 1王俊斌 1和占龙1
作者信息
- 1. 中国医学科学院/北京协和医学院 医学生物学研究所,云南省重大传染病疫苗研发重点实验室,昆明650118
- 折叠
摘要
Abstract
Objective To identify the P. mirabilis strain isolated from infant rhesus monkeys in the period of artificial feeding, and provide useful data for detection and identification of the bacteria in laboratory rhesus monkeys. Methods P. mirabilis strains isolated from infant rhesus monkeys were identified by cultural characteristics, colony morphology, staining, motility and biochemical test and serological test. Meanwhile, antibiotic sensitivity, virulence and toxin tests were conducted. Results The results of cultural characteristics, colony morphology, staining, biochemical and serological tests showed that the isolate was a strain of P. mirabilis. Effective therapeutic drugs were screened by antibiotic sensitivity test, and the disease was effectively controlled. Virulence tests showed that it is a highly pathogenic strain to mice. Conclusions The results of this study demonstrate that P. mirabilis isolated from infant monkeys is the pathogenic agent leading to their diarrhea and death. This bacteria strain is a conditional pathogen, which may cause some potential harm to researchers and laboratory rhesus monkeys. Although laboratory rhesus monkeys are allowed to be P. mirabilis carriers in our country, it is worth to pay high attention to the serious consequence of P. mirabilis infection, and it should be considered as an important issue.关键词
恒河猴/婴猴/奇异变形杆菌/分离鉴定Key words
Rhesus monkey ( Macaca mulatto), Infant/ Proteus mirabilis ( P. mirabilis)/ Isolation/Identification.分类
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赵远,杨凤梅,陈丽雄,禹文海,王俊斌,和占龙..人工哺育期腹泻婴猴奇异变形杆菌的分离与鉴定[J].中国比较医学杂志,2012,22(4):19-22,4.
