中国实用儿科杂志2012，Vol.27Issue(4)：285-288,4.
儿童非惊厥性癫痫持续状态12例临床特征与预后分析
The clinical features and prognosis of nonconvulsive status epilepticus in children: analysis of 12 cases
朱丽萍 1席加水 1王学禹 1聂翠丽1
作者信息
- 1. 山东大学附属省立医院小儿神经科,济南250021
- 折叠
摘要
Abstract
Objective To study the clinical and EEC features. therapeutic response and prognosis of nonconvulsive status epilepticus (NCSE)in children.Methods The clinical and EEG data of 12 children with NCSE were analyzed and therapeutic response and prognosis were followed up. Results The median onset age of symptoms was(6.22.72)yeais. The median duration of seizures was 35h. There were 3 children with absence status epilepsy (ASE)and 9 with psychomo-tor status epilepsy (PSE). The clinical presentations of NCSE included impairment of consciousness(n=12) .speech deterioration (n=9), behavior change (n=8), subtle motor findings such as eyelid twitching(n=5), illusion(n=2) , eating more food than ever or thirsty(n=2), and vegetative manifestation(n=l). The ictal EEG of NCSE showed slow activity with generalized spike-and-slow wave discharges and slow waves(n=3), and continuous or periodic focal discharges(n= 9), which was predominant with 9 or 5 activity(n=5), spike-and-slow wave discharges (n=4) .discharges in temporal region (n=3), out of temporal region (n=2) and temporal with other regions (n=4) .The control ratio of intravenous diazepam between ASE and PSE had no statistically significant difference(P > 0.05).Six children had cognitive impairment.Conclusion The main manifestations of NCSE are consciousness, speech deterioration and behavior change.The diagnosis can be made by ictal EEG.The prompt and effective manipulation of NCSE may reduce cognitive impairment.关键词
非惊厥性癫痫持续状态/脑电图/儿童Key words
nonconvulsive status epilepticus/ electroencephalogram/ children分类
医药卫生引用本文复制引用
朱丽萍,席加水,王学禹,聂翠丽..儿童非惊厥性癫痫持续状态12例临床特征与预后分析[J].中国实用儿科杂志,2012,27(4):285-288,4.
